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Sistem reproducator

Hirsutism. A, Mild facial hirsutism. B, Severe facial hirsutism (chin), which requires regular shaving. C, Severe hirsutism on chest.(B and C from Dunaif A,

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Homan A!, Scull" !#, et al. $he clinical, %iochemical and ovarian mor&hologic features in women with acanthosis nigricans and

masculini'ation.

Severe clitoromegal" resulting from a testosteronesecreting ovarian tumor. A, $heentire length of the clitoris is a&&roimatel" * cm (normal, + cm). B, $he

transverse diameter of the clitoris measures .- cm (normal, +./ cm).

Acanthosis nigricans. A, Moderate acanthosis nigricans (i.e., dar0ening and thic0eningof s0in) at the lateral lower fold of the nec0. 1otice facial hirsutism(side%urns) in the same &atient. B, Severe acanthosis nigricans in another &atient

with severe insulin resistance. (B courtes" of Dr. !. Ann 2ord, 3$ SouthwesternMedicalCenter, Dallas, $4.)

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A 5"earold &atient with &re&u%ertal androgen de6cienc" caused %" congenital anorchia %efore (A, C, and E) and after (B, D,and F) - "ears of testosteronetreatment. Before testosterone treatment, the &atient had features of eunuchoidism, characteri'ed %" infantile genitalia (small&enis and &oorl" develo&ed scrotum)7 lac0 of chest, &u%ic, and facial hair7 long arms and legs relative to height7 and &oorl" develo&ed muscle mass in the u&&er %od" withaccumulation of fat in the face, chest, and hi&s.

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After testosterone treatment, there was an increase in &enis si'e7 an increase in chest, &u%ic, and facial hair with scal& recessionand develo&ment of acne7 an increase inmuscle mass, &articularl" in the u&&er %od"7 and loss of fat in the face, chest, and hi&s. (8rom Matsumoto AM. $he testis. 9n: 8elig;, 8rohman rawHill7 ?:@-/-.)

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A -*"earold man with adult androgen de6cienc" caused %" h"&o&ituitarism who&resented with seual d"sfunction (reduced li%ido and erectile d"sfunction)7loss of chest, aillar", and &u%ic hair (A, B, and C)7 and g"necomastia (A). His &enisand testes were normal in si'e (B). He had normal facial hair (C), %ut his shavingfrequenc"was less.

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A /"earold man with severe androgen de6cienc" caused %" allmann s"ndrome(h"&ogonadotro&ic h"&ogonadism and anosmia) who &resented to a geriatricevaluation and management unit with functional and mo%ilit" disa%ilit" caused %"u&&er (A) and lower etremit" muscle wasting and severe %ac0 &ain from multi&leverte%ralcom&ression fractures (B) due to osteo&orosis. He was noted to have g"necomastia

and a%sence of chest, aillar", and &u%ic hair.

aria%ilit" in the degree of androgen de6cienc" manifested in men

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with linefelter s"ndrome. $he man on the left, who has classic */,44= linefelters"ndrome, demonstrates &re&u%ertal androgen de6cienc" with eunuchoidal %od"&ro&ortions,small &enis, s&arse chest and &u%ic hair, &oor muscle develo&ment, &re&u%ertalfat distri%ution, and ver" small testes (? m< %ilaterall"). $he man on the right,who has mosaic */,44=*@,4= linefelter s"ndrome, demonstrates normal %od"&ro&ortions,&enis si'e, and %od" hair %ut small testis si'e (E m< %ilaterall"). (8rom Sm"thCM, Bremner 2F. linefelter s"ndrome. Arch Intern Med. 55E7-E:5*.)

 $a%arcea #duard

Am'a Diana

Studenti an 999 ,Medicina Dentara ,3niversitatea Gradea

Bi%liogra6e

#ndocrinolog" #nc"clo&edia ,