“Petru Poni” al Academiei Romane Cercetare fundamentalăde ... 15.05.2014 r.pdfMisiune...

Institutul de Chimie Macromoleculară “Petru Poni” al Academiei Romane

Cercetare fundamentală de excelenţă şiorientări aplicative

Simpozionul “De la excelenţă la competitivitate: tehnologiile generice esenţiale”15 mai 2014 , Aula Academiei Române

Marcela [email protected]

Aleea Grigore Ghica Vodă, nr. 41A, 700487 Iaşi, Romania Tel.: +40‐232‐217454, Fax: +40‐232‐211299e‐mail: [email protected], http://www.icmpp.ro

Bogdan C. [email protected]

Misiune Indicatori de performanţă Cercetare fundamentală în ştiinţa polimerilor

Cercetare aplicativă, transfer tehnologic, microproducţie

Educaţie prin cercetare

Servicii

tehnologii industriale pentru: siliconi (uleiuri, elastomeri, răşini, adezivi, lubrifianţi), adezivi, poliuretani (piele sintetică, adezivi, unsori de blocare), schimbători de ioni

specializare prin intermediul programelor doctorale şi/sau postdoctorale a tinerilor cercetatori

peste 90 de teze de doctorat elaborate în institut în perioada 2003 – 2013

consultanţă în sinteza şi caracterizarea polimerilor şi materialelor polimere

activitate de transfer de cunoştinţe certificare de materiale polimere

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi

Rezultate obţinute în cercetare în 2013 lucrari publicate in reviste ISI din strainatate/reviste ISI din Romania: 257/55

capitole carti aparute in strainatate: 16 capitole carti aparute in alte edituri decat editura AR: 27 carti publicate in strainatate/in Romania: 1/4Brevete in Romania: 5 citari ale lucrarilor publicate anterior, in anul 2013: > 2490

Direcții de cercetare• Chimie supramoleculară, fizico‐chimia suprafeţelor• Materiale polimere din resurse regenerabile. Protecţia mediului. Conservarea energiei

• Materiale polimere proiectate pentru bioaplicaţii• Polimeri pentru aplicaţii de înaltă performanţă. Materiale nanodimensionate/ nanostructurate

Tehnologii generice esențiale• Nanotehnologii• Materiale avansate• Fotonică• Micro/nanoelectronică


Nanostructured azo‐polymeric films as support for cell cultures acting as 3D extracellular matrixSurface relief gratings as a result of trans‐cis isomersation of the azo‐benzene groups linked to apolyimide

High quality very thin films for electron‐beam lithography

Cells culture on thenanostructured film

Mater. Chem. Phys., in press

In “Functional organic nanostructures and thin organic films”, eds.: J. Reiche, B. Schulz, S. Schrader, B. Stiller (2004)

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Maria BRUMA([email protected])

Nanotehnologii

NN

n

O OC

CH3

CH3

SiCO

CO OC

N

N

O

N

N


Energy harvesting using polymers / Artificial muscles

Materi. Sci. Eng. C – Mater. Biol. Appl., accepted paper

Dr. Maria Cazacu([email protected])

Nanotehnologii

J. Biomed. Mater. Res. 101 A (6), 1661-1669 (2013)Sw

ellin

g de

gree

Temperature (oC)

uncomplexed

Complexed withDiclofenac

24 oC

45 oC

5 – 250 µm

Advanced self‐regulated drug delivery systems based on a sensor (pH‐sensitive units) and a delivery component (thermosensitive units)


(Bio)Nanotehnologii

Dr. Gheorghe [email protected]

NH2NH2

NH2NH2

NH2

NH2

D = Drug

NH3+NH3

+

NH3+NH3

+ NH3+

NH3+

DF

-OOC

DF

-OOC

DF

-OOC

DF

-OOC

DF

-OOC

DF

-OOC

D

D

D D

D

D

D

D D

D

D

NH3+NH3

+

NH3+NH3

+ NH3+

NH3+

DF

-OOC

DF

-OOC

DF

-OOC

DF

-OOC

DF

-OOC

DF

-OOC

D

D

D

D

D D

D

D

D

T>LCST

Biomaterials 31 (36), 9544-9553 (2010)

NIPAAm/AAm(mol %) 10/1.5 LCST (C) = 37.4 C (1500 g/mol)

37.8 C (3300 g/mol)

(pH = 7.4)

38 °C

35 °C

Intelligent devices for entrapment and release of drugs by a strict “on‐off” mechanism


(Bio)Nanotechnologies

Dr. Gheorghe [email protected]

5000

5000

4000 5000

4000

4000

50005000

4000

500040005000

5000

50004000

50004000

40005000

50004000500040004000

5000

01234567

1 2 3Lg

MElution volum (ml)

D2O

Glucoza(Mw = 180)

Mw = 1000Mw = 4000Mw = 5000Mw = 12000Mw = 25000Mw = 2000000a

Vp→ 4,44 ± 0,18 ml/g

T<LCST

01234567

1 2 3

LgM

Elution volum (ml)

D2O

Glucoza(Mw = 180)

Mw = 1000Mw = 4000 (Rg = 2.0 nm)Mw = 5000 (Rg = 2.3 nm)

Mw = 12000 (Rg = 3.6 nm)Mw = 25000Mw = 2000000

Vp→ 4,0 ± 0,12 ml/g

T>LCST

01234567

1 1.2 1.4 1.6 1.8 2 2.2 2.4

Lg M

Elution volum (ml)

a

D2O

Glucoza (Mw = 180)

Mw = 1000Mw = 4000 (Rg = 2.0 nm)Mw = 5000 (Rg = 2.3 nm)Mw = 12000 (Rg = 3.6 nm)Mw = 25000Mw = 2000000

Vp→ 4,56 ± 0,15 ml/g Vp → 4,18 ± 0,10 ml/g

01234567

1 1.2 1.4 1.6 1.8 2 2.2 2.4

LgM

Elution volum (ml)

D2O

Glucoza(Mw = 180)

Mw = 1000Mw = 4000Mw = 5000Mw = 12000Mw = 25000Mw = 2000000b b

T<LCST T>LCST

Low‐K polyimide films for dielectric interlayers

N

O

O

Si

CH3

CH3 O

O

NAr ONN

OO Ar O Si

CH3

CH3

n

10-1 100 101 102 103 104 105 106

2.7

2.8

2.9

3.0

3.1

3.2

Die

lect

ric c

onst

ant, '

f (Hz)

P-1 P-2 Kapton HN

Fluorinated polymers for flexible and transparent substrates in plastic electronics

Polymer‐based microactuators

O O

CF3 CF3

CF3

CF3

OONN

O

O

O

O n

Cerere brevet de inventie RO127096-A2/ 28 Feb 2012

Eur. Polym. J., 46, 1049–1062 (2010)

Eur. Polym. J., 50 200–213 (2014)


Nano‐electronica

Dr. Maria BRUMA([email protected])

Si Si

H

Si

H

Si

H H SiHH

SiH

HSi

H H

SiHH

SiH

HSiHH

SiH

H

T h,

a-Si-H2

Unstable cyclosilanes

Methylhydrosilyl-is a reactive group

Silicon nanoparticles

In situ Si nanoparticles by chemo‐restructuration

XPS Investigations of polyhydrosilane films showed elemental Si

AFM image of Si nanoparticles embedded within semiconductive polyhydrosilane matrix

OLEDs by microlitography

Macromol. Chem. Phys., 210, 2015-2021 (2010); Design monomers and polymers, 15(2), 127-136 (2012)

Polyhydrosilanes: PPIMC Route to Optoelectronics

Tests in Waker Co. Laboratories

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Liviu Sacarescu([email protected])

Nano‐electronica

Highly reactive polysilane

Tests ongoing in Australian Institute for Bioengineering and Nanotechnology/Australian National Fabrication Facility ‐QLD Node, The University of Queensland

Polym. International, 61(12), 1726-1732 (2012); J. Nanopart. Res., 13, 997-1005 (2011)

AgNP polymer matrix

Surface Enhanced Fluorescence

In situ

Photocatalytic process

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Liviu Sacarescu([email protected])

Nanosenzori

Liquid crystals for field effect transistors (FET) and light emitting diodes (LED)

S

S

S

H3C CH3 H3C CH3

II

S

S

S

S S

S

S C6H13

C6H13

I

S

S C6H13

S

S C6H13

III

S

S C6H13

S

S

O

C6H13

iV

I, 1C, 290 oC, 200x, 90 oC/min,phase transition nematic/smectic

II, 2H, 254 oC,400x,mosaic texture

III, 1H, 355 oC, 400x,fine texture

IV, 1C, 300 oC, 200x,Schlieren and focal conic

texture

: 10-4 - 10-3 cm2/Vs : 5 10-2 cm2/Vs, Tsub = 130 C

0 -5 -10 -15 -20 -25 -30

0-2-4-6-8

-10-12-14-16

I D [

A]

VD [V]

VG= 0V VG=-10V VG=-20V VG=-30V

LED imaging of II

high solid-state quantum yield (0.30 vs 0.63 in THF solution)

Optical microscopy micrography of the FET

Thin Solid Films, 515, 7318 – 7323 (2007), J. Optoelectr. Adv. Mater., 9 (5), 333 – 341 (2007), Liquid Crystals, 36, 21 – 32 (2009)


Micro‐ si nano‐electronica

Dr. Luminita MARIN([email protected])

Thermotropic liquid crystals for optoelectronic applicationsSemiconducting liquid crystals

OOCH3

CH3

SO

OCH

O NON OCH

SO

O

x

y

y=1-x

Good solubility in dipolar solventsHigh thermal stabilityThermotropic liquid crystalline behaviorSemiconducting properties

Continuous ordered films

P3: 1H, 225 oC, fine grainy texture

P4: 1H, 210 oC, fine texture

Polym. Adv. Technol., 17 (9-10), 664 – 672 (2006)Acta Materialia, 55 (2), 433 – 442 (2007) Thermotropic Liquid Crystalline Poly(azomethine-ether-sulfone)s. Synthesis and properties, Kerala, India (2010)


Micro‐ si nano‐electronica

Dr. Luminita MARIN([email protected])

Luminescent and electron‐transporting materials for opto‐electronic devices

Polyimide films for liquid crystals (LC) alignment layers in LCD displays

0.5

O NCO

O

O

O

CF3

CF3NO

NN

OO ONN

OCO O

CO

O

N

O

O

N

0.5n

N

O

O

N

O

O

O

O

N

O

O

NNN

OAr Ar Si O

CH3

CH3

Si

CH3

CH3

xy z n

-2.0 -1.5 -1.0 -0.5 0.0-0.0010

-0.0008

-0.0006

-0.0004

-0.0002

0.0000

I (m

A)

E (V)

1st

2nd

3rd

4th

5th

6th

NN

O

O

O

O

NH CO R1 CO NH

N

N

Ph

O R2

N

NO

Ph

NH

xy

nz

Dyes and polymers for phtovoltaic cells

-Peryleneimide based materials-Naphthylimide based materials-Thiophene-based materials

Dyes Pigments, 99 , 228-239 (2013) J. Polym. Res., in press

J. Mater .Sci ., 49,3080–3098 (2014)


Fotonica

Dr. Maria BRUMA([email protected])


An Alternative to Sustainable and Biodegradable Organic Electronics ‐Cotton Fabric ‐ Conjugated Polymers Composite

Dr. Ioan CIANGA([email protected])

Bull. Inst. Pol. Iasi, Tomul LVI (LX), Fasc. 3, Sectia Textile-Pielarie, pp. 58-66/ 2010Proceedings of International Symposium in Knitting and Apparel, Iasi, Romania 2010, pp1-11

0

200000

400000

600000

800000

1000000

1200000

1400000

1 2 3 4

Adhe

red cell/mg sample

E.coli

S.aureus

Materiale avansate

Functional micro‐ and nanoparticles based on PNAI building blocks / PNAI‐based gels

N O

RN

C

*H2C

OR

CH2

*n

drug release systemsuniform thin polymer films (electrode coating, biosensors)high selectivity membranes

self assembled core-shell microparticlesinterconnected pore structure

large channelsopen macropores

HEMA/NIPAAm/PROZO w/w/w - 1:1:1Biomacromolecules, 9, 1678 – 1683 (2008)

19oC 50oC

Swelling/deswelling kinetics


Materiale avansate

Acad. Bogdan C. SIMIONESCU([email protected])

Rev. Roum. Chim., 58 (2-3), 153-160 (2013); Int. J. Polym. Anal. Charact., 18: 189–198, (2013); Mater. Plast. 50 (2),71-78, (2013); J. Mater. Chem., 22, 9293-9300, (2012); Biomacromolecules, 13, 2680-2691, (2012); Biomacromolecules, 14, 3532-3541 (2013); Polym. Chem., 4, 2709-2723, (2013); J. Mater. Chem. B, 1, 4135-4145, (2013); Polymer (submitted).


Multifunctional Nanostructured Materials Based on Conjugated Polymers for Bioapplications

Dr. IOAN CIANGA([email protected])

Materiale avansate

0 1 2 3 4 50

100

200

300

400

q e, m

g M

B/g

cry

ogel

Number of cycles

Chem. Eng. J. 204-206, 198-209 (2012)Chem. Eng. J. 243, 572-590 (2014)

IPN cryogels based on polysaccharides and polyacrylamide used in separation processes of ionic species

Chem. Eng. J. 234, 211-222 (2013)

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Ecaterina Stela DRAGAN ([email protected])

MB+MO

IPNIPN, 1000x

MB+MO

IPNIPN, 1000x

MB+MO

IPNIPN, 1000x

MB+MO

IPNIPN, 1000x IPN+MBIPN+MBIPN+MBIPN+MB

MOMB+MO

IPNIPN, 1000x

MB+MO

IPNIPN, 1000x

MB+MO

IPNIPN, 1000x

MB+MO

IPNIPN, 1000x IPN+MBIPN+MBIPN+MBIPN+MBIPN+MBIPN+MBIPN+MBIPN+MB

MO

Materiale avansate

Bioresour. Technol. 101, 812-817, (2010); Chem. Eng. J. 160, 157-163, (2010); J. Hazard. Mater. 185, 447-455 (2011).

Enhanced sorption of heavy metal ions onto composite sorbents based on chitosan and zeolites (clinoptilolite)

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Ecaterina Stela DRAGAN ([email protected])

Materiale avansate

DNA dirrected decoration of single‐walled carbon nanotubes with gold nanoparticles

Electrochemical Reduction of Hydrogen Peroxide with Sol–gel–Prussian Blue composite electrode

PB 20 mM

PB 10 mM

Microchim Acta 181, 111–120 (2014)

»Significant enhancement of sensor sensitivity and stability

» Increase of anodic current due to the oxidation of monosaccharides at CNT‐NiCo‐oxide composite electrode

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Mariana Pinteala([email protected])

Materiale avansate

Hybrid nanocomposites based on block copolymers with end‐capped ZnO

The TEM images of ZnO nanoparticles (a), ZnO-PCEMA-Br-2 (b) and ZnO-PCEMA-b-

PEGMA-Br-2 polymer (c)

The AFM images of ZnO-PCEMA-b-PEGMA-Br-2 thin film

The fluorescence (b) spectra of ZnOnanoparticles (1), ZnO-BEI (2), ZnO-PCEMA-Br-2 (3) and ZnO-PCEMA-b-PEGMA-Br-2 (4) block copolymer (λexc=340 nm).

Cent. Eur. J. Chem. 11, 1492-1504 (2013)

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Emil Buruiana([email protected])

Materiale avansate

Hybrid photopolymers structured by UV‐light and femtosecond laser pulses

O

O

CH2

CH3

O

ONH

O

N

O

O

OH

N

ONH

OO

O

CH3

CH2

CH3 OSi N

HNH

OCH2

CH3

O

CH3

O

O

CH3

DC-MA

UAn-MA

UH-MA

Photo-DSC rate profiles and degree of conversion for DC-MA (), DC-MA/UH-MA (), UH-MA (*) (a) and (b) for UAn-MA (), UAn-MA/UH-MA ()

AFM images for the structures obtained by 2PP method starting from DC-MA/UH-MA(a) and UAn-MA/UH-MA (b)

SEM images for 2D structures based onDC-MA/UH-MA (c) and UAn-MA/UH-MA(d) (distance between lines: 50 μm;scanning velocity: 3 mm/s)

Soft Mater. 11, 1-8 (2013)*

* With co-authors from INFLPR – Bucuresti

Institutul de Chimie Macromoleculară “Petru Poni” Iaşi Dr. Emil Buruiana([email protected])

Materiale avansate

Aparatura disponibilăInstitutul este dotat cu echipamente de cercetare de ultimă generaţie la nivel european

• Preparare şi purificare/condiţionare

• Caracterizare de structură şi microstructură

Aparatura uzuală pentru sinteza de polimeri şi compuşi organici;Instalaţie de filme subţiri prin depunere în stare de vapori sau prin“spin coating”Aparate de liofilizare

Spectrometre RMN, FTIR, Raman Microscopie TEM, SEM-EDAX, AFMDifractometre de raze X


• Analiză dimensională

• Proprietăţi termice

• Proprietăţi optice

• Proprietăţi electrice

• Proprietăţi reologice

Zetasizer, Mastersizer, Elipsometru

Analiza termogravimetricăa, Microcalorimetrie diferenţială

Spectrometre UV-Viz, de fluorescenţă, Refractometre

Spectrometru dielectric, Electrometru

Reometre, Viscozimetre automate


Laboratoare acreditateAnaliza şi caracterizarea nano- şi microparticulelor• Laborator pentru testarea şi standardizarea materialelor polimerice nanometrice

(dimensiune şi formă, aria suprafeţei, dimensiunea porilor, densitate, chemisorptie şipotenţial zeta)

Evaluarea si certificarea materialelor polimere pentru/din ambalaje Laborator pentru prelucrarea polimerilor (extruder, blender si mixer), analiza directă

a reactiilor intermoleculare, determinarea grosimii filmelor ultra-subţiri, testaretracţiune/ compresie


CENTRU DE CERCETARI AVANSATE PENTRU BIONANOCONJUGATE SI BIOPOLIMERI

IntelCentru


Sinteza chimica si biosinteza

Investigatii la scaramicro‐ si nano

Simulare si imagistica moleculara „in silico”

Inginerie tisularasi vectori genetici non‐virali

BIONANOCONJUGATE

PARTICIPARE ÎN PROIECTE EUROPENE• FP3 – partener în 3 proiecte (COST – PECO, PECO – ERBIC – ICDCT, INCO – COPERNICUS – ERBIC)• FP5 – partener în 5 proiecte (2 INTAS, 1 CRAFT, 2 GROWTH)• FP6 – partener sau responsabil (peste 60 de parteneri şi un buget total de peste 1.2 mil. €)

• Apeluri 2003: partener în 3 NoE, 1 IP, 1 Marie Curie Tok)• Apeluri 2004: coordonator al proiectului RAINS; partener în 1 IP

• FP7 – partener în 5 proiecte

• COST – manager national în 6 Acţiuni COST• FONDURI STRUCTURALE ‐ 3 proiecte


Participǎri ȋn proiecte PC 7

• Added‐value from chemicals and polymers by new integrated separation, fractionation and upgrading technologies (AFORE), FP7‐NMP‐2008‐LARGE‐2‐228589 (Dr. Iuliana Spiridon)

• Bioactive highly porous and injectable scaffolds controlling stem cell recruitment proliferation and differentiation and enabling angiogenesis for cardiovascular engineered tissues (BIOSCENT), FP7‐NMP‐2007‐LARGE‐1‐214539 (Dr. ConstantinCiobanu)

• Mechanisms of interactions in nano‐scale of novel ionic lubricants with functional surfaces (MINILUBES), FP7‐PEOPLE‐2007‐1‐1‐ITN‐216011‐2 (Acad. Bogdan C. Simionescu)

• Strengthening the Romanian research capacity in Multifunctional Polymeric Materials (STREAM), FP7‐REGPOT‐2010‐1‐264115 (Dr. Valeria Harabagiu)


Participǎri ȋn proiecte finanţate din fonduri structurale• Fondul Social European – Program de burse postdoctorale „Cristofor I. Simionescu”,

POSDRU/89/1.5/S/55216 (Acad. Bogdan C. Simionescu) • POSCCE: Sinteza si studiul metalosiloxanilor polimerici – noi materiale de interes

pentru cataliza si nanostiinte (POLISILMET), ID 570, Cod SMIS – CSNR: 12473‐ 129/2010 (Dr. Maria Cazacu)

• POSCCE: Centru de Cercetǎri Avansate pentru Bionanoconjugate şi Biopolimeri, IntelCentru – ID 88, Nr. 03/01.03.2009; CodSMIS – CNRS 2213 (Dr. Mariana Pintealǎ)


COOPERARE INTERNAŢIONALĂ

• ICMPP are legături de colaborare ştiinţifică cu institute şi universităţi din Europa, Japonia, China, USA şi Canada.


Institutul de Chimie Macromoleculară “Petru Poni” al Academiei Romane

Cercetare fundamentală de excelenţă şiorientări aplicative

Simpozionul “De la excelenţă la competitivitate: tehnologiile generice esenţiale”15 mai 2014 , Aula Academiei Române

“Petru Poni” al Academiei Romane Cercetare fundamentalăde ... 15.05.2014 r.pdfMisiune...

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