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PARTICULARITATI FIZIOLOGICE ALE VRSTEI A TREIA

Procesul de mbtr!re s"u seesce# $resu$ue !%olu#!"&"ttmorfologic ct '! (uc#!o"l& " $r!c!$"lelor s!steme (uc#!o"le

- sc"de r"t" d!%!)!u!! celul"re- sc"de !%elul $roceselor met"bol!ce celul"re& cu

or!et"re s$re (")" c"t"bol!c- este ("%or!)"t $rocesul de d!struc#!e membr""r& cu

de*eer"re celul"r ulter!o"r- este ("%or!)"t d!stru*ere" l!)o)om"l- se mod!(!c $rocesele de s!te) $rote!c celul"r&

"soc!"t '! cu ted!#" de +decl!, " A-./ulu!- ted!t" l" "c!do)- "lter"re" re"c#!l!lor s!stemulu! !mu!t"r de $rotec#!e " sel(/ulu!0- se $"re c "r "%e" l" b") c" mec"!sm determ!"t scdere"

cu %rst" " c"$"c!t#!! (uc#!o"le " s!stemulu! edocr! "s"mblu '! "s!stemulu! er%os& cu e(ecte l" !%elul 1omeost")!e!& b")"te $e mod!(!c"re"

rece$t!%!t#!! $er!(er!ce '! " re"ct!%!t##!! #esutur!lor l" st!mul! er%o'! '!1ormo"l!

- l" !%elul S0.0 "$"r mod!(!cr! !%olut!%e& cu scdere"umrulu! de euro!0 Sut "(ect"te '! )oele eurosecreto"re d! S0.0&

$r!c!$"l 1!$ot"l"musul / sc"d secre#!!le euro1ormo!lor&eurotr"sm!#tor!lor& euromodul"tor!lor& cu e(ecte "su$r" s!stemulu!edocr!& " com$oete! s!m$"t!ce '! " termore*lr!!

- l" !%elul 1!$ot"l"musulu! se $"re c "r e2!st" u *eer"toreuroedocr! ude euro!! secretor! "c#!oe") $r! sem"le er%o"se '!

1ormo"le& !(lue#d "st(el celulele celorl"lte #esutur! "le or*"!smulu!- euro!! '! $!erd $ro*res!% dedr!tele '! "st(el '! s!"$sele& dec! c"$"c!t"te"me#!er!! '! re"l!)r!! de o! coe2!u!0 Asoc!"t '! cu scdere" $ro*res!% "cocetr"#!e! $l"sm"t!ce " %"so$res!e! este "lter"t (")" de cosol!d"re "memor!e!

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- $e com$oet" s!m$"t!c / "lter"re" c"t!t"t!% " e)!melor ce !ter%! s!te)" '! c"t"bol!)"re" c"tecol"m!elor0 Cosec!#" este scdere" %!*!le#e!& ""ct!%!t#!! or*"elor !tere& " "ct!%!t#!! se2u"le- scdere" rs$usur!lor 1!$ot"l"musulu! l" mec"!smele (eed b"c3 $o)!t!%e '!e*"t!%e $e "2ele edocr!e& res$ect!% 1!$ot"l"mus / 1!$o(!)- su$r"re"le& 1!$ot"l"mus / 1!$o(!) / t!ro!d& cu scdere" re"ct!%!t#!! l"stress0- $e com$oet" $"r"s!m$"t!c / scdere" e)!melor res$os"b!le de s!te)"

"cet!lcol!e!& mod s$ec!"l re*!u!le cort!c"le& cu "lter"re" memor!e! descurt dur"t '! cu "lterr! co*!t!%e cosecut!%e- l" !%elul "$"r"tulu! e2cretor "$"r $rocese de (!bro)"re re"l& c"re duc l"scdere" r"te! (!ltrr!! *lomerul"re '! dec! scdere" el!m!r!! d! or*"!sm "subst"#elor to2!ce "c!de 4"c!do)50 Asoc!ere" "(ectr!! (uc#!e! re"le 4scdere"c"$"c!t#!! de cocetr"re " r!!c1!lor5 cu scdere" cocetr"#!e! $l"sm"t!ce "A-6/ulu! determ! cre'tere" d!ure)e! 4$ol!ur!e5& cee" ce "re c" e(ectdes1!dr"t"re" celul"r $ro*res!%0 7od!(!c"re" (uc#!o"l " cetrulu! sete!4"lter"re euro"l5 determ! mod!(!c"re" se)"#!e! de sete 4sc"de5 '! sc"de"$ortul de "$- se "ccetue") des1!dr"t"re"0- l" !%el c"rd!o/%"scul"r se cost"t scdere" (or#e! de cotr"c#!e "m!oc"rdulu!& cee" ce duce l" scdere" %olumulu! s!stol!c '! " deb!tulu! c"rd!"c0-e "semee" sc"de met"bol!smul m!oc"rdulu!0/ "ccetu"re" $roceselor de "terosclero) duce l" scdere" el"st!c!t#!! $ere#!lor%"scul"r! '! l" cre'tere" re)!ste#e! $er!(er!ce / 6TA0- st"re sl"b de utr!#!e $r! edet"#!e $"r#!"l '! scdere" (uc#!!lor d!*est!%e&"soc!"t cu scdere" sector!e " 1ormo!lor de t!$ ""b!lo)"t& s$ec!"l " ST6/ulu!& duce l" "$"r!#!" str!! de subutr!#!e0 Cosec!#" / scdere" m"se! de #esutmuscul"r '! cre'tere" m"se! de #esut "d!$os '! co8uct!% l" !%elul s!stemulu!muscul"r0 -eo"rece #esutul muscul"r este u loc s$ec!(!c de ut!l!)"re '!met"bol!)"re " 1ormo!lor t!ro!d!e! "ce't!" u '! m"! e2erc!t tot"l!t"tee(ectele& cu "$"r!#!" "s$ectulu! de 1!$ot!ro!d!e / br"d!3!e)!e& br"d!$s!1!e&se)"#!e de (r!*& tulburr! de tr")!t !test!"l 4cost!$"#!e5& mod!(!cr! "rt!cul"rede t!$ "rtro)!c& mod!(!c"re" c"l!t#!! te*umetelor& de$udere de #esut "d!$os&

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"$"r!#!e de !(!ltr"te de t!$ edem"tos l" !%elul or*"elor !tere 4*reu"re""ct!%!t#!! "cestor"5scdere" "$ortulu! de C"& "soc!"t cu mod!(!cr!le met"bol!ce "le %!t0 - '! "re"bsorb#!e! !test!"le " C"& determ! "$"r!#!" 1!$oc"lcem!e!& scdere"cocetr"#!e! oso"se " C" / osteo$oro)0 L" se2ul (em!! se $!erde "$ro2 9:;d! m"s" oso"s " osulu! cort!c"l '! :