TULBURARI DE COAGULARE IN CIROZA HEPATICA.

PRINCIPII DE TRATAMENT

Mihai Olariu 1,Cristina Olariu

2,Dan Olteanu

2, Iulia Vasile

3

1.Institutul NaŃional de boli InfecŃioase”Prof.Dr.Matei Balş”

2.Universitatea de Medicină şi Farmacie”Carol Davila”,Bucureşti

3.Spitalul Universitar de UrgenŃă Bucureşti,Clinica Medicală I

Abstract

The liver is the site for synthesis of the majority of factors who have a role in coagulation

and fibrinolysis and,also, thrombopoietin, a hormon play a central role in megakariopoesis.In

cirrhosis,loss of hepatic parenchymal cells leads to decrease these factors.In addition portal

hypertension,renal failure,infections,low level of vitamin K and loss of vascular tone can

increase the risk of bleeding and hemoragic syndrome.In patients with impaired coagulation

but without clinical manifestation or who not need surgical interventions,isn’t necessary any

treatment.Is difficult to make a global strategy on the treatment because are many mechanism

involved.

Key words: coagulation,cirrhosis,hemoragic syndrom,treatment.