TULBURARI DE COAGULARE IN CIROZA HEPATICA. PRINCIPII … pdf/arhiva/Discobolul nr... · TULBURARI...
Transcript of TULBURARI DE COAGULARE IN CIROZA HEPATICA. PRINCIPII … pdf/arhiva/Discobolul nr... · TULBURARI...
TULBURARI DE COAGULARE IN CIROZA HEPATICA.
PRINCIPII DE TRATAMENT
Mihai Olariu 1,Cristina Olariu
2,Dan Olteanu
2, Iulia Vasile
3
1.Institutul NaŃional de boli InfecŃioase”Prof.Dr.Matei Balş”
2.Universitatea de Medicină şi Farmacie”Carol Davila”,Bucureşti
3.Spitalul Universitar de UrgenŃă Bucureşti,Clinica Medicală I
Abstract
The liver is the site for synthesis of the majority of factors who have a role in coagulation
and fibrinolysis and,also, thrombopoietin, a hormon play a central role in megakariopoesis.In
cirrhosis,loss of hepatic parenchymal cells leads to decrease these factors.In addition portal
hypertension,renal failure,infections,low level of vitamin K and loss of vascular tone can
increase the risk of bleeding and hemoragic syndrome.In patients with impaired coagulation
but without clinical manifestation or who not need surgical interventions,isn’t necessary any
treatment.Is difficult to make a global strategy on the treatment because are many mechanism
involved.
Key words: coagulation,cirrhosis,hemoragic syndrom,treatment.