Curriculum vitae Europass - Universitatea de Stiinte ...

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Curriculum vitae 1 INFORMAŢII PERSONALE Cristina Adriana DEHELEAN Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Piața Eftimie Murgu, nr. 2, 300041, Timișoara (România) telefon serviciu: 0256-204250, int. 1422 [email protected] EXPERIENŢA PROFESIONALĂ 2014 – PREZENT Profesor universitar, Coordonator Disciplina Toxicologie și Industria medicamentului Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Disciplina Toxicologie și Industria medicamentului Principalele activități și responsabilități: predarea cursurilor de Toxicologie, Metodologia cercetării științifice, Plante toxice, Farmacovigilență; Cursuri de pregătire postuniversitară, coordonator și lector în programul de master Medicamente de tip OTC, suplimente alimentare, cosmetice; coordonarea studenților în cadrul cercurilor științifice, workshop-urilor; pregătirea studenților pentru participarea la manifestări științifice naționale și internaționale; Coordonator doctoranzi Sectorul de activitate: învățământ superior 2020 - PREZENT Director al Consiliului pentru Studiile Universitare de Doctorat (CSUD) Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara Principalele activități și responsabilități: coordonare și monitorizare a Consiliului Studiilor Universitare de Doctorat Sectorul de activitate: învățământ superior 2020 Vicepreședinte- Consiliul Naţional de Atestare a Titlurilor, Diplomelor si Certificatelor Universitare (CNATDCU), Comisia Farmacie Gen. Berthelot 28-30, Sector 1, Bucureşti RO-010168, Romania, +40 214056206, www.cnatdcu.ro Principalele activități și responsabilități: Analiza tezelor de doctorat și a atestatelor de abilitare Sectorul de activitate: învățământ superior 2016 – PREZENT Vicepreședinte - Comitetul consultativ al Ministerului Sănătății - Comitetul pentru farmacologie clinică, toxicologie și dependență toxică Cristian Popişteanu, nr. 1-3, sector 1, Bucureşti RO-010024, Romania, +40 21 3072 500, www.ms.ro Principalele activități și responsabilități: activități consultative de specialitate în domeniul farmacologiei și toxicologiei Sectorul de activitate: sănătate 2012 – 2020 Decan Facultatea de Farmacie Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie Principalele activități și responsabilități: activități de coordonare și administrare a Facultății de Farmacie

Transcript of Curriculum vitae Europass - Universitatea de Stiinte ...

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INFORMAŢII PERSONALE Cristina Adriana DEHELEAN

Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Piața Eftimie Murgu, nr. 2, 300041, Timișoara (România) telefon serviciu: 0256-204250, int. 1422

[email protected]

EXPERIENŢA PROFESIONALĂ

2014 – PREZENT Profesor universitar, Coordonator Disciplina Toxicologie și Industria medicamentului Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Disciplina Toxicologie și Industria medicamentului

Principalele activități și responsabilități: predarea cursurilor de Toxicologie, Metodologia cercetării științifice, Plante toxice, Farmacovigilență; Cursuri de pregătire postuniversitară, coordonator și lector în programul de master Medicamente de tip OTC, suplimente alimentare, cosmetice; coordonarea studenților în cadrul cercurilor științifice, workshop-urilor; pregătirea studenților pentru participarea la manifestări științifice naționale și internaționale; Coordonator doctoranzi

Sectorul de activitate: învățământ superior

2020 - PREZENT Director al Consiliului pentru Studiile Universitare de Doctorat (CSUD) Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara

Principalele activități și responsabilități: coordonare și monitorizare a Consiliului Studiilor Universitare de Doctorat

Sectorul de activitate: învățământ superior

2020 Vicepreședinte- Consiliul Naţional de Atestare a Titlurilor, Diplomelor si Certificatelor Universitare (CNATDCU), Comisia Farmacie Gen. Berthelot 28-30, Sector 1, Bucureşti RO-010168, Romania, +40 214056206, www.cnatdcu.ro

Principalele activități și responsabilități: Analiza tezelor de doctorat și a atestatelor de abilitare

Sectorul de activitate: învățământ superior

2016 – PREZENT Vicepreședinte - Comitetul consultativ al Ministerului Sănătății - Comitetul pentru farmacologie clinică, toxicologie și dependență toxică Cristian Popişteanu, nr. 1-3, sector 1, Bucureşti RO-010024, Romania, +40 21 3072 500, www.ms.ro

Principalele activități și responsabilități: activități consultative de specialitate în domeniul farmacologiei și toxicologiei

Sectorul de activitate: sănătate

2012 – 2020 Decan Facultatea de Farmacie Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie

Principalele activități și responsabilități: activități de coordonare și administrare a Facultății de Farmacie

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Sectorul de activitate: învățământ superior

2009 - 2014 Conferențiar universitar Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Disciplina Toxicologie

Principalele activități și responsabilități: predarea cursurilor de Toxicologie, Metodologia cercetării științifice, Plante toxice, Farmacovigilență; coordonarea studenților în cadrul cercurilor științifice, workshop-urilor; pregătirea studenților pentru participarea la manifestări științifice naționale și internaționale

Sectorul de activitate: învățământ superior 2004 - 2009 Șef de lucrări

Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Disciplina Toxicologie

Principalele activități și responsabilități: activități didactice și de cercetare

Sectorul de activitate: învățământ superior

2002 - 2004 Asistent universitar Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Disciplina Dermatofarmacie și cosmetologie

Principalele activități și responsabilități: activități didactice și de cercetare

Sectorul de activitate: învățământ superior

1999 - 2002 Preparator universitar Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara, Facultatea de Farmacie, Disciplina Farmacie clinică

Principalele activități și responsabilități: activitate didactică – îndrumare lucrări practice, activitate de cercetare

Sectorul de activitate: învățământ superior

1996 - 1998 Farmacist Argefarm, Arad

Principalele activități și responsabilități: activitate de farmacist în farmacia de circuit deschis

Sectorul de activitate: sănătate

EDUCAŢIE ŞI FORMARE

2015 Abilitare în Farmacie, Conducător de doctorat, OMEC 4209/10/06.2015

Universitatea de Medicină și Farmacie "Victor Babeș" din Timișoara, Piața Eftimie Murgu nr. 2, 300041, Timișoara, România

2008 Farmacist primar, specialitatea Farmacie clinică - P1/007069, OMS 1971/2008

Ministerul Sănătăţii şi Familiei, Direcţia Generală Resurse Umane, Formare Profesională, Concursuri şi Examen

2004 Doctor în Farmacie - OMEC 3876/19.05.2004

Universitatea de Medicină și Farmacie “Gr. T. Popa” Iași, str. Universității nr. 16, Iași, România

2001 Farmacist specialist, specialitatea Farmacie clinică

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Ministerul Sănătăţii şi Familiei, Direcţia Generală Resurse Umane, Formare Profesională, Concursuri şi Examene

1998 - 2001 Farmacist rezident, specialitatea Farmacie clinică

Spitalul Județean 1 Timișoara, Bvd. Liviu Rebreanu nr. 156, Timișoara, România

1991 - 1996 Licență în Farmacie (Farmacist)

Universitatea de Medicină și Farmacie "Victor Babeș" din Timișoara, Piața Eftimie Murgu nr. 2, 300041, Timișoara, România

COMPETENŢE PERSONALE

LIMBA MATERNĂ ROMÂNĂ

Limbile străine cunoscute ÎNȚELEGERE VORBIRE SCRIERE

Ascultare Citire Participare la conversaţie

Discurs oral

engleză C2 C2 C2 C2 C2

franceză C2 C2 C1 C1 C2

Niveluri: A1 și A2: Utilizator elementar - B1 și B2: Utilizator independent - C1 și C2: Utilizator experimentat Cadrul european comun de referinţă pentru limbi străine

Competenţe de comunicare Excelente abilități de comunicare dobândite în urma activităților didactice susținute la diferite programe de studii de licență, de scurtă durată, postuniversitare; participarea la diverse conferințe naționale și internaționale; participarea în proiecte de cercetare cu parteneri din străinătate; prelegeri la diferite manifestări.

Capacitatea de a comunica constructiv în diferite situații sociale (de a tolera alte puncte de vedere, de a recunoaște responsabilitatea individuală și colectivă).

Competenţe organizaţionale/manageriale

Abiltăţi de coordonator de echipă, spirit organizatoric, capacitate de concentrare și planificare, implementare, coordonare, finalizare obiective sau indicatori de performanţă propuși în funcție de domeniu și activitate, capacitate de luare a deciziilor rapid și eficient, responsabilitate şi implicare în activităţile conduse; capacitatea de a lucra sub presiune, gestionarea timpului, rezolvarea conflictelor, auto-motivația și motivația colegilor, munca în echipă, creativitate, dinamism, disciplină, perseverență, gândire analitică, capacitatea de a construi relații , eficiență, adaptabilitate, deschidere, empatie.

Management universitar

1. Director CSUD

2. Membru al Senatului UMF “Victor Babeș” Timișoara

3. Decan Facultatea de Farmacie

4. Membru mai multe mandate in Consiliul Facultății de Farmacie și Consiliul Departamentului II

5. Coordonator al programului de studii masterale – Medicamente de tip OTC, suplimente alimentare, cosmetice (2015-prezent)

6. Coordonator disciplina de Toxicologie (2004-prezent)

7. Membru CNATDCU si Vicepreședinte

8. Membru ARACIS

Management de proiect

1. ERASMUS project 2019-1-RO01-KA203-063499 - Cooperation on innovation and exchange of good practice in the hypoglycemia diet for people with diabetes –

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responsabil proiect partener

2. CNFIS-FDI-2021-0498 “Dezvoltarea bazei de practica in domeniul plantelor medicinale a UMF Victor Babes Timisoara” – director de proiect

3. CNFIS-FDI-2019-0393 “Centru de dezvoltare profesională în domeniul produselor dermato-cosmetice pe bază de plante medicinale” – director de proiect

4. CNFIS – FDI – 2018 – 0159 „Centru de dezvoltare a abilităților practice în domeniul plantelor medicinale” – director de proiect

5. Axa 1 a POC – ANCS/ POC-A1- A1.1.4 – E-2015 “Utilizarea modelelor nutrigenomice pentru personalizarea tratamentelor dietetice in obezitate” (The use of nutrigenomic models for personalization of dietetic treatments in obesity) (NUTRIGEN) – manager științific

6. P III-C1-PCFI-2014/2015-03 “Noi abordări farmaceutice pentru modularea biodisponibilităţii unor flavonoide cu potenţial chemopreventiv pentru melanomul malign” (New pharmaceutical options for some Flavonoids bioavailability modulation with chemopreventiv potential in malignant melanoma) – director de proiect

7. UEFISCDI, bilateral project Romania-Hungary CT-665/22.04.2013 “Evaluarea impactului radiațiilor UV și al terapiei anti-tumorale asupra fibroblaștilor dermici și în cancerul cutanat experimental” (Impact assessment of UV radiation and antitumor therapy on dermal fibroblasts and in experimental skin cancer) – director de proiect

8. International Project Romania-China 198/2009 „Antioxidant activity of Chinese materia medica and its chemical composition” – director de proiect

9. TÁMOP-4.2.2-08/1-2008-0001 “International photobiological interdisciplinary research of the interactions of environmental and genomic factors, and processing new diagnostic and therapeutic methods” – responsabil proiect partener

10. Grant PN II 1257/2007 „Studiul implementarii unor bioproduşi antitumorali vegetali de tip triterpenic inclusiv prin formare de nanostructuri, in terapii cutanate, prin analiza eficacitate/toxicitate” (Study of implementation of vegetal antitumor bioproducts of triterpenic type by nanostructure formation, in skin therapies, by efficacy/toxicity analysis) – director de proiect

11. Grant INOVARE 69/2007 „Dezvoltarea unui produs fitofarmaceutic destinat terapiei adjuvante şi de prevenire a neoplaziei mamare” (Development of a phytopharmaceutical compound as adjuvant in treatment and prevention of breast cancer) – director de proiect

12. Grant CNCSIS AT 173/2007 „Elaborarea unor bioproduse cu compuşi triterpenici şi ciclodextrine şi analiza eficacitate/nocivitate a acestora in patologii cutanate” (Elaboration of bioproducts with triterpenic compounds and cyclodextrins and their efficacy/toxicity analysis in skin pathologies) – director de proiect

13. Evaluator proiecte CNCSIS si UEFISCDI

Manifestări științifice

1. Coordonator al platformei online FITOSCIENCE – www.umft.ro 2. Coordonator program - Summer School Dermo-cosmetic products based on

medicinal plants, 17-19 July 2019 Timișoara 3. Coordonator program - 1st International Summer School of Medicinal Plant

Pharmaco-Toxicology, 2-13 July 2018 Timișoara, România 4. Coordonator program WORKSHOP - Dermo-cosmetic products as formulations.

safety testing of cosmetic products, 13-14 June, 2019, Timișoara, România 5. Coordonator program WORKSHOP - Plantele medicinale în prezent – incidență,

compoziție și utilizare (Medicinal Plants at present - incidence, composition and use), 16-17 Otober, 2018, Timișoara, România

6. Coordonator program WORKSHOP - Siguranța produselor pe bază de plante medicinale (Safety of medicinal plants products), 22-23 November, 2018, Timișoara, România

7. Organizator al evenimentelor științifice: National Symposiums TIMISOARA 2005,

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ANEXA I. ACTIVITATEA DE CERCETARE ȘTIINȚIFICĂ

I.1 PROIECTE DE CERCETARE

2008, TIMMEDICA 2011, workshop în cadrul proiectului bilateral Romania-China, workshop în cadrul proiectului bilateral Romania-Ungaria

Competenţe dobândite la locul de muncă

Foarte bună cunoștere a cadrului legislativ corelat învățământului superior și cercetării științifice. Calitatea de expert în publicarea articolelor științifice situate în zonele roșu și galben (conform clasificării UEFISCDI), capacitatea de a realiza colaborări multidisciplinare la nivel national și international (a se vedea anexele).

▪ Evaluator ARACIS, Comisia (C12) Științe medicale, domeniul Sănătate–registrul național

▪ conducătorul Filialei locale EUROTOX și membru în colegiul conducător la Societății de Științe Farmaceutice locale

▪ membru al primei Comisii de Asigurare a Calității la nivelul UMFVBT

▪ competențe în evaluarea de proiecte naționale și internaționale, recenzor la reviste de specialitate iar raportat la brevetele aplicate responsabilitate în proprietate intelectuală.

▪ 2008 – Evaluator CNCSIS, Domeniul Toxicologie

Competenţe digitale ▪ abilități utilizator experimentat, inclusiv curs Microsoft Project Advanced 2011

INFORMAŢII SUPLIMENTARE

▪ Coordonator principal / Centrul de evaluări farmaco-toxicologice – Facultatea de Farmacie, Universitatea de Medicină și Farmacie “Victor Babeș” din Timișoara

▪ Reviewer invitat: Food and Chemical Toxicology, Journal of AOAC International, Natural Product Research, Molecules

▪ Membru în colectivul editorial: Experimental and Therapeutic Medicine, EC Pharmacology and Toxicology, Research and Clinical Medicine, World Research Journal Of Medicinal &Aromatic Plants

▪ Membru: SSFR, EUROTOX, AMAPSEEC, SRCC Premii ▪ Perioada 2012-2020 – peste 40 de premii acordate de către UEFISCDI în cadrul

competiției Premierea rezultatelor cercetării

▪ Medalia de aur și Diploma de excelență - The international salon of inventiveness pro invent, XIVen Edition, 23-25 Martie 2016, Cluj-Napoca, România

▪ Medalia de aur și Diploma de excelență, Euro-invent, 19-21 Mai, 2016, Iași, România

▪ Medalia de aur 45th International Geneva Salon of Inventions, 29 Martie – 2 Aprilie 2017, Elveția

▪ Medalia de bronz - International invention-innovation showroom Traian Vuia Timișoara, 25-27 Mai 2016, Timișoara, România

▪ Medalia de aur, Tesla fest, International Conference on Innovation and Intellectual Property, 12-15 Octombrie 2018, Novi Sad, Serbia

▪ Certificat oficial de merit internațional pentru contribuția la inovare și cooperare internațională excelentă, Tesla fest, International Conference on Innovation and Intellectual Property, 12-15 Octombrie 2018, Novi Sad, Serbia

▪ Medalia de argint – In vitro antibacterial activity of some plant essential oils from Cupressaceae family – Euroinvent, European Exhibition of Creativity and Innovation – Xth edition, 17-19 Mai 2018, Iași, România

▪ MEDIS 2006, 2012, 2013, Szeged, Hungary 2009 (premii ale studenților coordonați)

▪ Premiul I pentru merite deosebite în activitatea didactică în cadrul Facultății de Medicină a Universității de Medicină și Farmacie “Victor Babeș” Timișoara (2015)

ANEXE

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Nr crt

Titlul proicetului Poziția Perioada

1. CNFIS-FDI-2021-0498 Title: Dezvoltarea bazei de practică în domeniul plantelor medicinale a UMF Victor Babeș Timișoara / Development of the practice base in the field of medicinal plants of the "Victor Babes" University of Medicine and Pharmacy Timisoara

Manager Mai 2021 – Decembrie

2021

2.

PN-III-P1-1.1-TE-2019-2134, acronym BAPRONIO Titlu: Redarea către piața dermocosmetica a unei formulari topice moderne cu acid betulinic încorporat in proniozomi / Delivery to the dermocosmetic market of a modern topical formulation with betulinic acid encapsulated in proniosomes

Membru 2020 - 2022

3. 1EXP/1233/30.01.2020 Title: Lupeol as bioactive natural compound in the local treatment of wounds and inflammation from mild to severe pathologies: experimental evaluations and market pre-proposal

Membru 2020 - 2021

4.

PN-III-P1-1.1-TE2019-0130 Hidrogeluri inovatoare pe bază de micele polimerice ca sisteme de cedare pentru uleiul esențial de oregano: o abordare farmaceutică avansată pentru gestionarea papiloamelor cutanate / Innovative hydrogels based on polymeric micelles as release systems for oregano essential oil: an advanced pharmaceutical approach to papilloma management cutaneous

Membru 2020- 2023

5.

PN-III-P2-2.1-PED2019-3067 Nanobiostructuri inovatoare bazate pe nanoparticule ferimagnetice conjugate cu ciclodextrine pentru cresterea eficacitatii si reducerea toxicitatii in terapia cancerului prin hipertermie SP-magnetica / Innovative nanobiostructures based on ferromagnetic nanoparticles conjugated with cyclodextrins to increase efficacy and reduce toxicity in cancer therapy by SP-magnetic hyperthermia

Membru 2020- 2023

6.

PN-III-P1-1.1- PD-2019-1231 Noi perspective privind chemoprevenția cancerului cutanat: evaluarea acidului maslinic și al unui derivat de acid maslinic încorporați în nanoemulsii / New perspectives on skin cancer chemoprevention: evaluation of maslinic acid and a maslinic acid derivative incorporated in nanoemulsions

Mentor 2020-2023

7. ERASMUS project 2019-1-RO01-KA203-063499 - Cooperation on innovation and exchange of good practice in the hypoglycemia diet for people with diabetes

Manager proiect

partener 2019 - 2021

8. CNFIS-FDI-2019-0393 “Centru de dezvoltare profesională în domeniul produselor dermato-cosmetice pe bază de plante medicinale / Center for professional development in the field of dermato-cosmetic products based on medicinal plants” – project director”

Manager Mai 2019 – Decembrie

2019

9. CNFIS – FDI – 2018 – 0159 „Centru de dezvoltare a abilităților practice în domeniul plantelor medicinale / Center for the development of practical skills in the field of medicinal plants”

Manager Mai 2018 – Decembrie

2018

10. CNFIS – FDI – 2018 – 0459 D2- Internationalization Membru Mai 2018 – Decembrie

2018

11. PN-III-P1-1.1-PD-2016-1982 – Proiecte de Cercetare Postdoctorală, competiția 2016 ”Noi perspective privind mecanismul de acțiune al acidului betulinic ca agent antimelanom/ New insights into the antimelanoma mechanism of action of betulinic acid”

Mentor 2017-2019

12. PN-III-P4-ID-PCE-2016-0765 “Materiale avansate pe bază de nanoparticule magnetice de oxizi de fier obținute prin combustie și citotoxicitatea acestora utilizată în terapia cancerului”

Membru 2017-2019

13. Axa 1 a POC – ANCS/ POC-A1- A1.1.4 – E-2015 “Utilizarea modelelor nutrigenomice pentru personalizarea tratamentelor dietetice in obezitate” (The use of nutrigenomic models for personalization of dietetic treatments in obesity) (NUTRIGEN)

Manager științific

2016-2019

14. PN-III-P2-2.1-BG-2016-0354, No 115/2016 „Formulări pe bază de betulină și nanoparticule de aur în combaterea procesului de îmbătrânire a pielii” (Formulations based on betulin and gold nanoparticles to combat skin aging)

Membru 2016-2018

15. PN-III-P2-2.1-BG-2016- 0455, No 122/2016 „Formulări de avangardă pe bază de eugenol nanocapsulat cu adresabilitate în medicina dentară” (Avant-garde formulations based on eugenol nanocapsules addressable in dentistry)

Membru 2016-2018

16. PN-II-PT-PCCA, No110/2014 “Recuperarea avansată a produselor utile din deşeurile de catalizatori uzaţi” (Advanced recovery of useful products from used catalysers waste) (REMACAT)

Membru 2014-2017

17.

UEFISCDI Bilateral project Romania – France no. 791/30.06.2014 “Obtinerea micro-cristalelor de triterpene pentaciclice si studiul modificarilor lor” (Obtaining pentacyclic triterpene micro - crystals and pharmaceutical toxicology study of their changes in experimental models)

Membru 2014-2016

18.

UEFISCDI Bilateral project Romania-France RO-FR 789/30.06.2014 “Nanostructuri cu aurone, chalcone şi extracte vegetale standardizate: dezvoltarea unui nou prototip de agent chemopreventiv şi antiinflamator” (Nanostructures with aurones, chalcones and standardized vegetal extracts: development of a new prototype of chemopreventiv and anticancer agent)

Membru 2014-2016

19. P III-C1-PCFI-2014/2015-03 “Noi abordări farmaceutice pentru modularea biodisponibilităţii unor flavonoide cu potenţial chemopreventiv pentru melanomul malign” (New pharmaceutical options for some Flavonoids bioavailability modulation with chemopreventiv potential in malignant melanoma)

Manager 2014-2016

20.

UEFISCDI, bilateral project Romania-Hungary CT-665/22.04.2013 “Evaluarea impactului radiațiilor UV și al terapiei anti-tumorale asupra fibroblaștilor dermici și în cancerul cutanat experimental” (Impact assessment of UV radiation and antitumor therapy on dermal fibroblasts and in experimental skin cancer)

Manager 2013-2014

21. UEFISCDI, bilateral projects Romania-Hungary CT-674/22.04.2013 “Evaluarea unor formulări Membru 2013-2014

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farmaceutice moderne obținute prin complexarea unor triterpene pentaciclice cu derivați polizaharidici funcționalizați” (Evaluation of some modern pharmaceutical formulations obtained by complexation of of some pentacyclic triterpenes with polysacharides functionalised derivatives)

22. SEE-ERA.NET PLUS Joint project 139/01 reference number: ERA 139/01 ”Systems to reduce mycotoxins contamination of cereals and medicinal plants in order to preservation native species and traditional products in Romania-Serbia-Croatia area”

Membru 2010-2012

23. International Project Romania-China 198/2009 „Antioxidant activity of Chinese materia medica and its chemical composition”

Manager 2009-2010

24. TÁMOP-4.2.2-08/1-2008-0001 “International photobiological interdisciplinary research of the interactions of environmental and genomic factors, and processing new diagnostic and therapeutic methods”

Manager partener român

2009-2011

25. Project CNCSIS IDEI 2284 „Diagnosticarea cancerului şi monitorizarea terapeutica prin tehnici Raman ultrasensibile” (Cancer diagnosis and therapeutical monitoring by ultrasensitive Raman spectroscopic techniques)

Membru 2008-2011

26.

Grant PN II 1257/2007 „Studiul implementarii unor bioproduşi antitumorali vegetali de tip triterpenic inclusiv prin formare de nanostructuri, in terapii cutanate, prin analiza eficacitate/toxicitate” (Study of implementation of vegetal antitumor bioproducts of triterpenic type by nanostructure formation, in skin therapies, by efficacy/toxicity analysis)

Manager 2007-2010

27. Grant INOVARE 69/2007 „Dezvoltarea unui produs fitofarmaceutic destinat terapiei adjuvante şi de prevenire a neoplaziei mamare” (Development of a phytopharmaceutical compound as adjuvant in treatment and prevention of breast cancer)

Manager 2007-2010

28. Grant CNCSIS AT 173/2007 „Elaborarea unor bioproduse cu compuşi triterpenici şi ciclodextrine şi analiza eficacitate/nocivitate a acestora in patologii cutanate” (Elaboration of bioproducts with triterpenic compounds and cyclodextrins and their efficacy/toxicity analysis in skin pathologies)

Manager 2007-2008

29. Project CEEX cod 30/2006 „Evaluarea conţinutului de metale grele din sol cu ajutorul plantelor bioindicatoare şi valorificarea acestora în scopuri terapeutice” (The evaluation of soil heavy metals content using bioindicators plants and their therapeutic added value)

Membru 2006-2008

30. Proiect CEEX ET 35/2006 „Biotehnologii pentru obţinerea de bioproduse rezultate prin valorificarea indicatorilor vegetali ai metalelor din sol” (Biotechnologies for bioproducts preparation using the valorification of vegetal indicators of metals from soil)

Membru 2006-2008

31. Project CEEX 10/ 2005 „Studiul bioactivitaţii sinergice a alimentelor funcţionale antioxidante in reversabilitatea sindromului metabolic” (The study of the synergic bioactivity of functionalized antioxidant aliments in reversibility of metabolic syndrome) (BIOTECH)

Membru 2005-2007

32. Leonardo da Vinci, Agreement No. RO-2004-PL 93056-TD Training of „European Phytotherapists for Discovery of New Medications”

Membru 2005

I.2 IMPACTUL ACTIVITĂȚII DE CERCETARE I.2.1 CAPITOLE DE CARTE ÎN EDITURI INTERNAȚIONALE – 10, Elsevier (2 capitole – 2019, 2018), InTech (6 capitole – 2018, 2017, 2015),

Studium press LLC, Houston, USA (2 capitole – 2014) I.2.2 PUBLICAȚII ISI (WOS) – 306, 218 ARTICOLE ISI FULL TEXT, 23 REVIEW, 6 PROCEEDINGS PAPER, 56 – MEETING ABSTRACT,

2 BOOK CHAPTER, 1 EDITORIAL MATERIAL I.2.3 PREMII PENTRU ACTIVITATEA DE CERCETARE – peste 40 I.2.4 INDICE HIRSH – 26, TOTAL CITĂRI – 2003 (fără autocitări) I.3 ÎNCADRARE PUBLICAȚII ȘTIINȚIFICE – WOS

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I.4 COLABORĂRI INTERNAȚIONALE I.4.1 GERMANIA

Clin Goethe Univ, Inst Gen Pharmacol & Toxicol, Pharmazentrum Frankfurt ZAFES, D-60590 Frankfurt, Germany

Goethe Univ Frankfurt, Inst Biochem Pathobiochem 1, D-60590 Frankfurt, Germany

Martin Luther Univ Halle Wittenberg, Dept Organ Chem, Kurt Mothes Str 2, D-06120 Halle, Saale, Germany

Univ Freiburg, Dept Dermatol, Hauptstr 7, D-79104 Freiburg, Germany

Signalhaus Freiburg, BIOSS Ctr Biol Signalling Studies, Schanzlestr 18, D-79104 Freiburg, Germany Articole științifice (WOS): 1 – Nutrients (2020 – IF 5.719); 3 - International Journal of Molecular Sciences (2019 – IF 4.556); 1 - European

Journal of Pharmaceutics and Biopharmaceutics (2019 – IF 4.604); 1 - International Journal of Experimental Pathology (2015 – IF 2.125); 1 – PLOS ONE (2015 – IF 3.057); 1 – Biological Chemistry (2013 – IF 2.689) I.4.2 STATELE UNITE ALE AMERICII

Northeastern Univ, Sch Pharm, Dept Pharmaceut Sci, Boston, MA 02115 USA

Rutgers State Univ, New Jersey Inst Food Nutr & Hlth, 61 Dudley Rd, New Brunswick, NJ 08901 USA

Wright State Univ, Dept Chem, Dayton, OH 45435 USA Articole științifice (WOS): 1 – Frontiers in Pharmacology (2020 - IF 5.811); 1 - Environmental Toxicology and Pharmacology (2019 - IF 3.292);

1 - European Journal of Pharmaceutics and Biopharmaceutics (2019 – IF 4.604); 1 - Food and Chemical Toxicology (2018 - IF 3.775); 2 – Journal of Biomedical Nanotechnology (2013 – IF 7.578, 2011 – IF 4.216); 1 – Chemistry Central Journal (2012 – IF 1.312) I.4.3 GRECIA

Univ Crete, Fac Med, Dept Forens Sci & Toxicol, Iraklion 71003, Crete, Greece

Univ Crete, Med Sch, Lab Clin Virol, Iraklion 71003, Crete, Greece Articole științifice (WOS): 1 - Journal of Clinical Medicine (2020 - IF 4.241); 2 - Environmental Toxicology and Pharmacology (2019 - IF

3.292); 2 - Frontiers in Pharmacology (2018 - IF 3.845, 2017 – IF 3.831); 2 - Food and Chemical Toxicology (2018 - IF 3.775; 2016 – IF 3.778); 1 - International Journal of Oncology (2017 – IF 3.333); Molecular Medicine Reports (2017 – IF 1.922); 1 - International Journal of Molecular Medicine (2017 – IF 2.784); 1 - Oncology Reports (2017 – IF 2.976) I.4.4 UNGARIA

Univ Szeged, Inst Pharmaceut Technol & Regulatory, Szeged, Hungary

Univ Szeged, Dept Pharmacodynam & Biopharm, Szeged, Hungary

Gedeon Richter Plc, H-1103 Budapest, Hungary

Dr Derm Clin Antiaging Dermatol Aesthet Laser & P, H-1026 Budapest, Hungary

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Univ Szeged, Dept Dermatol & Allergol, H-6720 Szeged, Hungary

Univ Szeged, Dept Oral Biol & Expt Dent Res, H-6720 Szeged, Hungary Articole științifice (WOS): 3 - Molecules (2020 IF 4.411, 2019 – 3.267, 2015 – IF 2.465); 1 – Nutrients (2019 – IF 4.546); 1 – Frontiers in

Chemistry (2019 – IF 3.693); 4 - International Journal of Molecular Sciences (2018 – IF 4.183, 2015 – IF 3.257, 2014 – IF 2.862, 2012 – IF 2.464); 1 – Biomedical Optics Express (2016 – IF 3.337); I.4.5 FRANȚA

Aix Marseille Univ, Fac Pharm, 27 Jean Moulin Blvd, F-13385 Marseille 5, France

Université Université de Lorraine, Bvd des Aiguillettes 54506 Vandoeuvre les Nancy, France Articole științifice (WOS): 1 – Planta Medica (2015 - IF 1.990, Meeting Abstract). Proiect bilateral RO-FR: UEFISCDI Bilateral project Romania – France nr.791/30.06.2014 I.4.6 ANGLIA

Aston Univ, Pharmaceut Dept, Sch Life & Hlth Sci, Birmingham B4 7ET, W Midlands, England

Middlesex Univ London, Dept Nat Sci, London, England Articole științifice (WOS): 1 - Environmental Toxicology and Pharmacology (2019 - IF 3.292); 1 - Frontiers in Pharmacology (2018 - IF

3.845); 1 - International Journal of Molecular Medicine (2017 – IF 2.784) I.4.7 AUSTRIA

Univ Vienna, Dept Struct & Computat Biol, Max F Prutz Labs, Vienna, Austria

Univ Vienna, Fac Phys, Quantum Opt Quantum Nanophys & Quantum Informat, Vienna, Austria Articole științifice (WOS): 1 – Frontiers in Pharmacology (2020 - IF 5.811) I.4.8 ITALIA

University of Calabria, Department of Pharmacy, Health and Nutritional Science, via Pietro Bucci, 87036 Arcavacata di Rende (CS), Italy

Proiect ERASMUS: Cooperation on innovation and exchange of good practice in the hypoglycemia diet for people with diabetes

ERASMUS K2, project nr. 2019-1-RO01-KA203-063499

ANEXA II. ACTIVITATEA DIDACTICĂ II.1 Coordonare lucrări de licență și disertație: peste 60 – lucrări de licență (perioada 2012-2020), 25 – lucrări de disertație în cadrul programului de master Medicamente de tip OTC, sulimente alimentare, cosmetice; 9 – lucrări de disertație în cadrul programului de master Formularea și evaluarea produsului dermatocosmetic II.2 Cărți și monografii – 6 de specialitate; actualizarea cursurilor în format ppt anual după ultimele noutăți apărute în domeniu II.3 Coordonator program VADA – an universitar 2017/2018 – 2 studenți; an universitar 2018/2019 – 3 studenți; an universitar 2019/2020 – 5 studenți, an universitar 2020-2021 – 4 studenți; an universitar 2021-2022 – 4 studenți II.4 Coordonator program master – Medicamente de tip OTC, suplimente alimentare, cosmetice II.5 Coordonare cercuri științifice studențești – Evaluarea farmacotoxicologică a unor produse vegetale cu acţiune terapeutică (2017 – www.umft.ro) II.6 Participarea în comisii din procesul educaţional admitere/ licenţă/ rezidențiat/ comisii de evaluare instituţională ale UMFVBT

ANEXA III. LISTA PUBLICAȚII

2022 1. Marinescu AR, Lăzureanu V, Laza R, Musta V, Nicolescu N, Cuț TG, Dehelean C, Oancea C, Licker M. Association between

ribotype and clinical form of enterocolitis with C. difficile in Western Romania: A 2-year study. Exp Ther Med. 2022 Jan;23(1):22. doi: 10.3892/etm.2021.10944. IF 2.447

2. Pilut CN, Manea A, Macasoi I, Dobrescu A, Georgescu D, Buzatu R, Faur A, Dinu S, Chioran D, Pinzaru I, Hancianu M, Dehelean C, Malița D. Comparative Evaluation of the Potential Antitumor of Helleborus purpurascens in Skin and Breast Cancer. Plants (Basel). 2022 Jan 12;11(2):194. doi: 10.3390/plants11020194. IF 3.935

3. Dinu S, Craciunescu EL, Macasoi I, Chioran D, Rivis M, Vlad D, Milutinovici RA, Marcovici I, Dolghi A, Moaca A, Dinu DC, Dehelean C, Popa M. Toxicological Assessment of an Acrylic Removable Orthodontic Appliance Using 2D and 3D In Vitro Methods. Materials (Basel). 2022 Feb 4;15(3):1193. doi: 10.3390/ma15031193. IF 3.623

4. Tanase A, Manea A, Scurtu AD, Bratu LM, Chioran D, Dolghi A, Alexoi I, AAbed H, Lazureanu V, Dehelean CA. The “Invisible Enemy” SARS-CoV-2: Viral Spread and Drug Treatment. Medicina. 2022; 58(2):261. https://doi.org/10.3390/medicina58020261 IF 2.430

2021

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1. Dolghi A, Buzatu R, Dobrescu A, Olaru F, Popescu GA, Marcovici I, Pinzaru I, Navolan D, Cretu OM, Popescu I, Dehelean CA. Phytochemical Analysis and In Vitro Cytotoxic Activity against Colorectal Adenocarcinoma Cells of Hippophae rhamnodies L., Cymbopogon citratus (D.C.) Stapf, and Ocimum basilicum L. Essential Oils. Plants (Basel). 2021 Dec 14;10(12):2752. doi: 10.3390/plants10122752. IF 3.935

2. Pinzaru I, Chioibas R, Marcovici I, Coricovac D, Susan R, Predut D, Georgescu D, Dehelean C. Rutin Exerts Cytotoxic and Senescence-Inducing Properties in Human Melanoma Cells. Toxics. 2021 Sep 19;9(9):226. doi: 10.3390/toxics9090226 IF 4.146

3. Blidisel A, Marcovici I, Coricovac D, Hut F, Dehelean CA, Cretu OM. Experimental Models of Hepatocellular Carcinoma-A Preclinical Perspective. Cancers (Basel). 2021 Jul 21;13(15):3651. doi: 10.3390/cancers13153651. IF 6.639

4. Hut E-F, Radulescu M, Pilut N, Macasoi I, Berceanu D, Coricovac D, Pinzaru I, Cretu O, Dehelean C. Two Antibiotics, Ampicillin and Tetracycline, Exert Different Effects in HT-29 Colorectal Adenocarcinoma Cells in Terms of Cell Viability and Migration Capacity. Current Oncology. 2021; 28(4):2466-2480. https://doi.org/10.3390/curroncol28040225. IF 3.677

5. Pop D, Buzatu R, Moacă E-A, Watz CG, Cîntă Pînzaru S, Barbu Tudoran L, Nekvapil F, Avram Ș, Dehelean CA, Crețu MO, Nicolov M, Szuhanek C, Jivănescu A. Development and Characterization of Fe3O4@Carbon Nanoparticles and Their Biological Screening Related to Oral Administration. Materials. 2021; 14(13):3556. https://doi.org/10.3390/ma14133556. IF 3.623

6. Ghiƫu A, Pavel IZ, Avram S, Kis B, Minda D, Dehelean CA, Buda V, Folescu R, Danciu C. An In Vitro-In Vivo Evaluation of the Antiproliferative and Antiangiogenic Effect of Flavone Apigenin against SK-MEL-24 Human Melanoma Cell Line. Anal Cell Pathol (Amst). 2021 Jun 21;2021:5552664. doi: 10.1155/2021/5552664. IF 2.916

7. Coricovac D, Dehelean CA, Pinzaru I, Mioc A, Aburel O-M, Macasoi I, Draghici GA, Petean C, Soica C, Boruga M, Vlaicu B, Muntean MD. Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line. International Journal of Molecular Sciences. 2021; 22(9):4870. https://doi.org/10.3390/ijms22094870. IF 2.916

8. Moacă E-A, Watz C-G, Socoliuc V, Racoviceanu R, Păcurariu C, Ianoş R, Cîntă-Pînzaru S, Tudoran LB, Nekvapil F, Iurciuc S, Șoica C, Dehelean C-A. Biocompatible Magnetic Colloidal Suspension Used as a Tool for Localized Hyperthermia in Human Breast Adenocarcinoma Cells: Physicochemical Analysis and Complex In Vitro Biological Profile. Nanomaterials. 2021; 11(5):1189. https://doi.org/10.3390/nano11051189. IF 5.076

9. Simu S, Marcovici I, Dobrescu A, Malita D, Dehelean CA, Coricovac D, Olaru F, Draghici GA, Navolan D. Insights into the Behavior of Triple-Negative MDA-MB-231 Breast Carcinoma Cells Following the Treatment with 17β-Ethinylestradiol and Levonorgestrel. Molecules. 2021 May 8;26(9):2776. doi: 10.3390/molecules26092776. IF 4.412

10. Fabricky MMC, Gabor AG, Milutinovici RA, Watz CG, Avram Ș, Drăghici G, Mihali CV, Moacă EA, Dehelean CA, Galuscan A, Buzatu R, Duma VF, Negrutiu ML, Sinescu C. Scaffold-Type Structure Dental Ceramics with Different Compositions Evaluated through Physicochemical Characteristics and Biosecurity Profiles. Materials (Basel). 2021 Apr 27;14(9):2266. doi: 10.3390/ma14092266. IF 3.623

11. Guran K, Buzatu R, Pinzaru I, Boruga M, Marcovici I, Coricovac D, Avram S, Poenaru M, Susan M, Susan R, Radu D, Dehelean CA. In Vitro Pharmaco-Toxicological Characterization of Melissa officinalis Total Extract Using Oral, Pharynx and Colorectal Carcinoma Cell Lines. Processes. 2021; 9(5):850. https://doi.org/10.3390/pr9050850. IF 2,847

12. Lombrea A, Scurtu AD, Avram S, Pavel IZ, Turks M, Lugiņina J, Peipiņš U, Dehelean CA, Soica C, Danciu C. Anticancer Potential of Betulonic Acid Derivatives. Int J Mol Sci. 2021 Apr 1;22(7):3676. doi: 10.3390/ijms22073676 IF 5.924

13. Sipos S, Moacă E-A, Pavel IZ, Avram Ş, Crețu OM, Coricovac D, Racoviceanu R-M, Ghiulai R, Pană RD, Şoica CM, Borcan F, Dehelean CA, Crăiniceanu Z. Melissa officinalis L. Aqueous Extract Exerts Antioxidant and Antiangiogenic Effects and Improves Physiological Skin Parameters. Molecules. 2021; 26(8):2369. https://doi.org/10.3390/molecules26082369. IF 4.412

14. Pancu DF, Scurtu A, Macasoi IG, Marti D, Mioc M, Soica C, Coricovac D, Horhat D, Poenaru M, Dehelean C. Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening. Antibiotics. 2021; 10(4):401. https://doi.org/10.3390/antibiotics10040401. IF 4.639

15. Iftode A, Drăghici GA, Macașoi I, Marcovici I, Coricovac DE, Dragoi R, Tischer A, Kovatsi L, Tsatsakis AM, Cretu O, Dehelean C. Exposure to cadmium and copper triggers cytotoxic effects and epigenetic changes in human colorectal carcinoma HT-29 cells. Exp Ther Med. 2021 Jan;21(1):100. doi: 10.3892/etm.2020.9532. IF 2.447

16. Antal DS, Ardelean F, Jijie R, Pinzaru I, Soica C, Dehelean C. Integrating Ethnobotany, Phytochemistry, and Pharmacology of Cotinus coggygria and Toxicodendron vernicifluum: What Predictions can be Made for the European Smoketree? Front Pharmacol 2021, 12, 746. DOI=10.3389/fphar.2021.662852. IF 5.811

17. Cepeha CM, Paul C, Borlea A, Fofiu R, Borcan F, Dehelean CA, Ivan V, Stoian D. Shear-Wave Elastography-Diagnostic Value in Children with Chronic Autoimmune Thyroiditis. Diagnostics (Basel). 2021 Feb 5;11(2):248. doi: 10.3390/diagnostics11020248. IF 3.706

18. Dehelean CA, Marcovici I, Soica C, Mioc M, Coricovac D, Iurciuc S, Cretu OM, Pinzaru I. Plant-Derived Anticancer Compounds as New Perspectives in Drug Discovery and Alternative Therapy. Molecules. 2021 Feb 19;26(4):1109. doi: 10.3390/molecules26041109. IF 4.412

19. Şoica C, Voicu M, Ghiulai R, Dehelean C, Racoviceanu R, Trandafirescu C, Roșca OJ, Nistor G, Mioc M, Mioc A. Natural Compounds in Sex Hormone-Dependent Cancers: The Role of Triterpenes as Therapeutic Agents. Front Endocrinol (Lausanne). 2021 Jan 21;11:612396. doi: 10.3389/fendo.2020.612396. IF 5.555

20. Danciu C, Cioanca O, Watz Farcaș C, Hancianu M, Racoviceanu R, Muntean D, Zupko I, Oprean C, Tatu C, Paunescu V, Proks M, Diaconeasa Z, Soica C, Pinzaru I, Dehelean C. Botanical Therapeutics (Part II): Antimicrobial and In Vitro Anticancer Activity against MCF7 Human Breast Cancer Cells of Chamomile, Parsley and Celery Alcoholic Extracts. Anticancer Agents Med Chem. 2021;21(2):187-200. doi: 10.2174/1871520620666200807213734. IF 2.507

21. Pinzaru I, Tanase A, Enatescu V, Coricovac D, Bociort F, Marcovici I, Watz C, Vlaia L, Soica C, Dehelean C. Proniosomal Gel for Topical Delivery of Rutin: Preparation, Physicochemical Characterization and In Vitro Toxicological Profile Using 3D Reconstructed Human Epidermis Tissue and 2D Cells. Antioxidants (Basel). 2021 Jan 10;10(1):85. doi: 10.3390/antiox10010085. IF 6.313

22. Pinzaru I, Sarau C, Coricovac D, Marcovici I, Utescu C, Tofan S, Popovici RA, Manea HC, Pavel IE, Soica C, Dehelean C. Silver Nanocolloids Loaded with Betulinic Acid with Enhanced Antitumor Potential: Physicochemical Characterization and In Vitro Evaluation. Nanomaterials (Basel). 2021 Jan 9;11(1):152. doi: 10.3390/nano11010152. IF 5.076

23. Borcan F, Len A, Dehelean CA, Dudás Z, Ghiulai R, Iftode A, Racoviceanu R, Soica CM. Design and Assessment of a Polyurethane Carrier Used for the Transmembrane Transfer of Acyclovir. Nanomaterials (Basel). 2020 Dec 28;11(1):51. doi: 10.3390/nano11010051. IF 5.076

2020

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1. Lombrea A, Antal D, Ardelean F, Avram S, Pavel IZ, Vlaia L, Mut AM, Diaconeasa Z, Dehelean CA, Soica C, Danciu C. A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil. Int J Mol Sci. 2020 Dec 17;21(24):9653. doi: 10.3390/ijms21249653. IF 5.924

2. Szuhanek CA, Watz CG, Avram Ș, Moacă EA, Mihali CV, Popa A, Campan AA, Nicolov M, Dehelean CA. Comparative Toxicological In Vitro and In Ovo Screening of Different Orthodontic Implants Currently Used in Dentistry. Materials (Basel). 2020 Dec 13;13(24):5690. doi: 10.3390/ma13245690. IF 3.623

3. Alexa VT, Szuhanek C, Cozma A, Galuscan A, Borcan F, Obistioiu D, Dehelean CA, Jumanca D. Natural Preparations Based on Orange, Bergamot and Clove Essential Oils and Their Chemical Compounds as Antimicrobial Agents. Molecules. 2020 Nov 24;25(23):5502. doi: 10.3390/molecules25235502. IF 4.412

4. Dumbrava D, Popescu LA, Soica CM, Nicolin A, Cocan I, Negrea M, Alexa E, Obistioiu D, Radulov I, Popescu S, Watz C, Ghiulai R, Mioc A, Szuhanek C, Sinescu C, Dehelean C. Nutritional, Antioxidant, Antimicrobial, and Toxicological Profile of Two Innovative Types of Vegan, Sugar-Free Chocolate. Foods. 2020 Dec 11;9(12):1844. doi: 10.3390/foods9121844. IF 4.35

5. Ghiulai R, Roşca OJ, Antal DS, Mioc M, Mioc A, Racoviceanu R, Macaşoi I, Olariu T, Dehelean C, Creţu OM, Voicu M, Şoica C. Tetracyclic and Pentacyclic Triterpenes with High Therapeutic Efficiency in Wound Healing Approaches. Molecules. 2020 Nov 26;25(23):5557. doi: 10.3390/molecules25235557. IF 4.412

6. Maghiari AL, Coricovac D, Pinzaru IA, Macașoi IG, Marcovici I, Simu S, Navolan D, Dehelean C. High Concentrations of Aspartame Induce Pro-Angiogenic Effects in Ovo and Cytotoxic Effects in HT-29 Human Colorectal Carcinoma Cells. Nutrients. 2020 Nov 24;12(12):3600. doi: 10.3390/nu12123600. IF 5.719

7. Enătescu VR, Kalinovic R, Dehelean CA, Giurgi-Oncu C, Hogea LM, Ifteni P, Vlad G, Neda-Stepan O, Simu M, Bedreag OH, Marinescu I, Hutanu D, Enătescu I, Nussbaum LA. The efficacy of clonidine in the pharmacological management of alcohol withdrawal syndrome: preliminary results. Farmacia, 2020, 68(6), 1069-1074. IF 1.433

8. Faur A, Watz C, Moacă EA, Avram Ş, Borcan F, Pinzaru I, Iftode A, Nicolov M, Popovici RA, Raica M, Szuhanek CA, Dehelean C. Correlations on Phenolic Screening Related to In Vitro and In Ovo Assessment of Ocimum basilicum L. Hydro-Alcoholic Extracts Used as Skin Active Ingredient. Molecules. 2020 Nov 20;25(22):5442. doi: 10.3390/molecules25225442. IF 4.412

9. Kis B, Avram S, Pavel IZ, Lombrea A, Buda V, Dehelean CA, Soica C, Yerer MB, Bojin F, Folescu R, Danciu C. Recent Advances Regarding the Phytochemical and Therapeutic Uses of Populus nigra L. Buds. Plants (Basel). 2020 Oct 29;9(11):1464. doi: 10.3390/plants9111464. IF 2.762

10. Cepeha CM, Paul C, Borlea A, Borcan F, Fofiu R, Dehelean CA, Stoian D. The Value of Strain Elastography in Predicting Autoimmune Thyroiditis. Diagnostics (Basel). 2020 Oct 27;10(11):874. doi: 10.3390/diagnostics10110874. IF 3.706

11. Popa A, Dehelean C, Calniceanu H, Watz C, Brad S, Sinescu C, Marcu OA, Popa CS, Avram S, Nicolov M, Szuhanek CA. A Custom-Made Orthodontic Mini-Implant-Effect of Insertion Angle and Cortical Bone Thickness on Stress Distribution with a Complex In Vitro and In Vivo Biosafety Profile. Materials (Basel). 2020 Oct 27;13(21):4789. doi: 10.3390/ma13214789 IF 3.623

12. Racoviceanu R, Trandafirescu C, Voicu M, Ghiulai R, Borcan F, Dehelean C, Watz C, Aigner Z, Ambrus R, Coricovac DE, Cîrcioban D, Mioc A, Szuhanek CA, Şoica C. Solid Polymeric Nanoparticles of Albendazole: Synthesis, Physico-Chemical Characterization and Biological Activity. Molecules. 2020 Nov 4;25(21):5130. doi: 10.3390/molecules25215130. IF 4.412

13. Groşan, Alexandra, Vari, Camil-Eugen, Ştefănescu, Ruxandra, Danciu, Corina, Pavel, Ioana Zinuca, Dehelean, Cristina, Man, Adrian, David, Remona Eliza, Vlase, Laurian and Muntean, Lucia Daniela. "Antibacterial and antitumor activity of the species ." Revista Romana de Medicina de Laborator, vol.28, no.4, 2020, pp.405-417. https://doi.org/10.2478/rrlm-2020-0031 IF 1.027

14. Eremici, Ivana; Dumitru, Catalin; Navolan, Dan; Craina, Marius; Ivan, Viviana; Borcan, Florin; Dehelean, Cristina A.; Mozos, Ioana; Stoian, Dana. 2020. "Diagnostic Value of Different Risk-Stratification Algorithms in Solid Breast Lesions" Appl. Sci. 10, no. 19: 6943. https://doi.org/10.3390/app10196943 IF 2.679f

15. Bojin LA, Georgescu M, Cojocaru C, Pascariu MC, Purcarea VL, Ivan MV, Puiu M, Dehelean C, Serb AF, Sisu E, Penescu MN. Structural investigation of raw and modified glycans by Maldi-Tof mass spectrometry. Farmacia, 2020, 68(5), 891-897. IF 1.433

16. Buda V, Brezoiu AM, Berger D, Pavel IZ, Muntean D, Minda D, Dehelean CA, Soica C, Diaconeasa Z, Folescu R, Danciu C. Biological Evaluation of Black Chokeberry Extract Free and Embedded in Two Mesoporous Silica-Type Matrices. Pharmaceutics. 2020 Sep 1;12(9):838. doi: 10.3390/pharmaceutics12090838. IF 6.321

17. Macașoi I, Pavel IZ, Moacă AE, Avram Ș, David VL, Coricovac D, Mioc A, Spandidos DA, Tsatsakis A, Șoica C, Dumitrașcu V, Dehelean

C. Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate. Oncol Rep. 2020 Sep;44(3):1169-1183. doi: 10.3892/or.2020.7666. IF 3.906

18. Circioban, D; Ledeti, I; Suta, LM; Vlase, G; Ledeti, A; Vlase, T; Varut, R; Sbarcea, L; Trandafirescu, C; Dehelean, C. Instrumental analysis and molecular modelling of inclusion complexes containing artesunate. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 2020 DOI: 10.1007/s10973-020-09975-3 IF 4.626

19. Balea, TS; Parvu, AE; Parvu, M; Vlase, L; Dehelean, CA; Pop, TI. Antioxidant, Anti-Inflammatory and Antiproliferative Effects of theVitis viniferaL. var. Feteasca Neagra and Pinot Noir Pomace Extracts. FRONTIERS IN PHARMACOLOGY 2020 Volume: 11, Article Number: 990, DOI: 10.3389/fphar.2020.00990 IF 5.811

20. Moatar, AE; Vlad, CS; Vlad, DC; Verdes, DM; Filimon, MN; Bloju, O; Borcan, F; Dehelean, CA; Dumitrascu, V. Evaluation of antiproliferative potential of myrmecodia pendans and its activity on IL-8 secretion in colon cancer cell. FARMACIA 2020 Volume: 68 Issue: 4 Pages: 710-714, DOI: 10.31925/farmacia.2020.4.17 IF 1.433

21. Dehelean, CA; Lazureanu, V; Coricovac, D; Mioc, M; Oancea, R; Marcovici, I; Pinzaru, I; Soica, C; Tsatsakis, AM; Cretu, O. SARS-CoV-2: Repurposed Drugs and Novel Therapeutic Approaches—Insights into Chemical Structure—Biological Activity and Toxicological Screening, JOURNAL OF CLINICAL MEDICINE, 2020, 9, 2084; doi:10.3390/jcm9072084. IF 4.242

22. Circioban, D; Ledeti, A; Vlase, G; Vlase, T; Dehelean, C; Ledeti, I. Thermal stability and kinetic degradation study for dihydroartemisinin. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 2020, DOI: 10.1007/s10973-020-09902-6. IF 4.626

23. Fecker, R; Buda, V; Alexa, E; Avram, S; Pavel, IZ; Muntean, D; Cocan, I; Watz, C; Minda, D; Dehelean, CA; Soica, C; Danciu, C. Phytochemical and Biological Screening of Oenothera biennis L. Hydroalcoholic Extract. BIOMOLECULES 2020, Volume: 10 Issue: 6 Article Number: 818, DOI: 10.3390/biom10060818. IF 4.879

24. Circioban, D; Ledeti, A; Vlase, G; Ledeti, L; Vlase, T; Varut, R; Pavel, LZ; Dehelean, C. Preparation, physicochemical characterization and biological activity evaluation of some inclusion complexes containing artesunate. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 2020, Volume: 141 Issue: 3 Pages: 1041-1051 DOI: 10.1007/s10973-020-09763-z. IF 4.626

25. Farcas CG; Macasoi I; Pinzaru I; Chirita M; Chirita Mihaila MC; Dehelean C; Avram S; Loghin F; Mocanu L; Rotaru V; Ieta A; Ercuta A; Coricovac D. Controlled Synthesis and Characterization of Micrometric Single Crystalline Magnetite with Superparamagnetic Behavior and Cytocompatibility/Cytotoxicity Assessments. FRONTIERS IN PHARMACOLOGY 2020; 11:410. DOI: 10.3389/fphar.2020.00410 IF 6.4

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26. Borlea, A; Borcan, F; Sporea, I; Dehelean, CA; Negrea, R; Cotoi, L; Stoian D. TI-RADS Diagnostic Performance: Which Algorithm is Superior and How Elastography and 4D Vascularity Improve the Malignancy Risk Assessment. DIAGNOSTICS (Basel). 2020 Mar 26;10(4). pii: E180. DOI: 10.3390/diagnostics10040180. IF 3.706

27. Cotoi, L; Borcan, F; Sporea, I; Amzar, D; Schiller, O; Schiller, A; Dehelean, CA; Pop, GN; Borlea, A; Stoian, D. Thyroid Pathology in End-Stage Renal Disease Patients on Hemodialysis. DIAGNOSTICS (Basel). 2020 Apr;10(4), 245 DOI: 10.3390/diagnostics10040245. IF 3.11

28. Enatescu VR; Dehelean CA; Nussbaum LA; Hogea L; Homorogan C; Enatescu I; Papava I; Marinescu I; Ifteni P; Simu M; Catalin M; Giurgi-Oncu C; Sirbu IO. Study On Tolerability And Efficacy Of Paliperidone Palmitate, Olanzapine Pamoate And Risperidone Long Acting Injection In A Romanian Sample Of Patients With Schizophrenia. FARMACIA, 2020, 68(2):242-249. DOI: 10.31925/farmacia.2020.2.8 IF 1.433

29. Putz, AM; Ianasi, C; Dudas, Z; Coricovac, D; Watz, C; Len, A; Almasy, L; Sacarescu, L; Dehelean, C. SiO2-PVA-Fe(acac)(3) Hybrid Based Superparamagnetic Nanocomposites for Nanomedicine: Morpho-textural Evaluation and In Vitro Cytotoxicity Assay. MOLECULES, 2020, 25(3), Article Number: 653, DOI: 10.3390/molecules25030653 IF 4.412

30. Simu, GM; Atchana, J; Soica, CM; Coricovac, DE; Simu, SC; Dehelean, CA (autor coresp). Pharmaceutical Mixtures: Still A Concern for Human and Environmental Health. CURRENT MEDICINAL CHEMISTRY, 2020, 27(1):121-153, Special Issue: SI, DOI: 10.2174/092986732566681108094222 IF 4.53

31. Antal, DS; Ardelean, F; Avram, S; Pavel, IZ; Danciu, C; Soica, C; Dehelean C. Flavonolignans: One Step Further in the Broad-Spectrum Approach of Cancer. ANTICANCER AGENTS MED CHEM. 2020 Jan 23. DOI: 10.2174/1871520620666200124112649. IF 2.507

2019 1. Cotoi, L; Borcan, F; Sporea, I; Amzar, D; Schiller, O; Schiller, A; Dehelean, CA; Pop, GN; Stoian, D. Shear Wave Elastography in

Diagnosing Secondary Hyperparathyroidism. DIAGNOSTICS, 2019, 9(4), Article Number: 213, DOI: 10.3390/diagnostics9040213 IF 3.11

2. Kis, B; Ifrim, FC; Buda, V; Avram, S; Pavel, IZ; Antal, D; Paunescu, V; Dehelean, CA; Ardelean, F; Diaconeasa, Z; Soica, C; Danciu, C.

Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer. INTERNATIONAL JOURNAL

OF MOLECULAR SCIENCES, 2019, 20(23), Article Number: 5905, DOI: 10.3390/ijms20235905 IF 4.556

3. Trandafirescu, C; Ledeti, I; Soica, C; Ledeti, A; Vlase, G; Borcan, F; Dehelean, C; Coricovac, D; Racoviceanu, R; Aigner, Z. Albendazole-

cyclodextrins binary systems Thermal and spectral investigation on drug-excipient interaction. JOURNAL OF THERMAL ANALYSIS AND

CALORIMETRY, 2019, 138(5):3039-3054, DOI: 10.1007/s10973-019-08326-1 IF 2.731

4. Vlad, CS; Vlaia, L; Vlaia, V; Dumitrascu, V; Filimon, MN; Popescu, R; Cimporescu, A; Dehelean, C; Onwubiko, CE; Daliborca, CV.

Chromatographic analysis and antibacterial potential of extracts of Gnetum Africanum. FARMACIA, 2019, 67(6):1083-1090, DOI:

10.31925/farmacia.2019.6.22 IF 1.607

5. Draghici, GA; Dehelean, C; Pinzaru, I; Bordean, DM; Borozan, A; Tsatsakis, AM; Kovatsi, L; Nica, D. Soil copper uptake by land snails:

A semi-field experiment with juvenile Cantareus aspersus snails. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2019,

72:UNSP 103243, DOI: 10.1016/j.etap.2019.103243 IF 3.292

6. Moaca, EA; Pavel, IZ; Danciu, C; Crainiceanu, Z; Minda, D; Ardelean, F; Antal, DS; Ghiulai, R; Cioca, A; Derban, M; Simu, S; Chioibas,

R; Szuhanek, C; Dehelean, CA. Romanian Wormwood (Artemisia absinthium L.): Physicochemical and Nutraceutical Screening.

MOLECULES, 2019, 24(17):3087, DOI: 10.3390/molecules24173087 IF 3.267

7. Duca, A; Sturza, A; Moaca, EA; Negrea, M; Lalescu, VD; Lungeanu, D; Dehelean, CA (autor coresp); Muntean, DM; Alexa, E.

Identification of Resveratrol as Bioactive Compound of Propolis from Western Romania and Characterization of Phenolic Profile and

Antioxidant Activity of Ethanolic Extracts. MOLECULES, 2019, 24(18):3368, DOI: 10.3390/molecules24183368 IF 3.267

8. Stoian, D; Borcan, F; Petre, I; Mozos, I; Varcus, F; Ivan, V; Cioca, A; Apostol, A; Dehelean, CA. Strain Elastography as a Valuable

Diagnosis Tool in Intermediate Cytology (Bethesda III) Thyroid Nodules. DIAGNOSTICS, 2019, 9(3):119, DOI:

10.3390/diagnostics9030119 IF 3.11

9. Chioibas, R; Borcan, F; Dehelean, CA; Soica, CM. Comparative Characterization of Different Samples Containing Nano-ZnO Particles

with Applicability in Topical Therapies. MATERIALE PLASTICE, 2019, 56(3):652-656 IF = 1.393

10. Draghici, GA; Dehelean, CA; Pinzaru, I; Bordean, DM; Pop, G; Nica, DV. An 112-Days Experiment on Dietary Cadmium Retention in

Hepatopancreas in Adult Cantareus aspersus Snails. REVISTA DE CHIMIE, 2019, 70(8):2803-2804 IF 1.755

11. Circioban, D; Pavel, IZ; Ledeti, A; Ledeti, I; Danciu, C; Dehelean, C. Cytotoxic Activity Evaluation on Breast Cells of Guest-host Complexes

Containing Artemisinin. REVISTA DE CHIMIE, 2019, 70(8):2843-2846 IF 1.755

12. Popovici RA; Vaduva D; Pinzaru I; Dehelean CA; Farcas CG; Coricovac D; Danciu C; Popescu I; Alexa E; Lazureanu V; Stanca HT. A

comparative study on the biological activity of essential oil and total hydro-alcoholic extract of Satureja hortensis L. EXPERIMENTAL AND

THERAPEUTIC MEDICINE, 2019, 18(2): 932–942. DOI: 10.3892/etm.2019.7635 IF 1.785

13. Boda, D; Dehelean, C. Immuno-dermatological processes involved in chronic skin diseases: Highlights of the Second Conference of the

Romanian Society for Immuno-Dermatology, Bucharest, September, 2018. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019,

18(2):873-874, DOI: 10.3892/etm.2019.7690, Publisher Spandidos Publ LTD, Pob 18179, Athens, 116 10, Greece IF 1.785

14. Iman, V; Taculescu, A; Dehelean, C; Paunescu, V. Magnetic Nanoparticles (MNPs) Influence on SK-BR3 Breast Cancer Cell Line - in

vitro Study. REVISTA DE CHIMIE, 2019, 70(7):2452-2455 IF 1.755

15. Pavel, IZ; Csuk, R; Danciu, C; Avram, S; Baderca, F; Cioca, A; Moaca, EA; Mihali, CV; Pinzaru, I; Muntean, DM; Dehelean, CA.

Assessment of the Antiangiogenic and Anti-Inflammatory Properties of a Maslinic Acid Derivative and its Potentiation using Zinc Chloride.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20(11):2828, DOI: 10.3390/ijms20112828 IF 4.556

16. Moacă EA, Mihali CV, Macaşoi IG, Racoviceanu Băbuţă R, Şoica C, Dehelean CA, Păcurariu C, Florescu S. Fe3O4@C Matrix with

Tailorable Adsorption Capacities for Paracetamol and Acetylsalicylic Acid: Synthesis, Characterization, and Kinetic Modeling.

MOLECULES, 2019, 24(9). pii: E1727. DOI: 10.3390/molecules24091727 IF 3.267

17. Tuta-Sas, I; Proks, M; Paunescu, V; Pinzaru, I; Sas, I; Coricovac, D; Moaca, A; Dehelean, C. Thymus Vulgaris Extract Formulated as

Cyclodextrin Complexes: Synthesis, Characterization, Antioxidant Activity and in Vitro Cytotoxicity Assessment. FARMACIA, 2019,

67(3):442-451, DOI: 10.31925/farmacia.2019.3.10 IF 1.607

18. Moacă EA, Farcaş C, Coricovac D, Avram S, Mihali CV, Drâghici GA, Loghin F, Păcurariu C, Dehelean C. Oleic Acid Double Coated

Fe₃O₄ Nanoparticles as Anti-Melanoma Compounds with a Complex Mechanism of Activity-In Vitro and In Ovo Assessment. J BIOMED

NANOTECHNOL. 2019, 15(5):893-909. DOI: 10.1166/jbn.2019.2726 IF 4.483

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19. Ghițu A, Schwiebs A, Radeke HH, Avram S, Zupko I, Bor A, Pavel IZ, Dehelean CA, Oprean C, Bojin F, Farcas C, Soica C, Duicu O,

Danciu C. A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory

Phytocompound. NUTRIENTS. 2019, 11(4). pii: E858. DOI: 10.3390/nu11040858 IF 4.546

20. Coșarcă SL, Moacă EA, Tanase C, Muntean DL, Pavel IZ, Dehelean C. Spruce and beech bark aqueous extracts: source of polyphenols,

tannins and antioxidants correlated to in vitro antitumor potential on two different cell lines, WOOD SCIENCE AND TECHNOLOGY, 2019,

53(2): 313-333, DOI: 10.1007/s00226-018-1071-5 IF 2.109

21. Nicolov M, Ghiulai RM, Voicu M, Mioc M, Duse AO, Roman R, Ambrus R, Zupko I, Moaca EA, Coricovac DE, Farcas C, Racoviceanu RM,

Danciu C, Dehelean CA, Soica C. Cocrystal Formation of Betulinic Acid and Ascorbic Acid: Synthesis, Physico-Chemical Assessment,

Antioxidant, and Antiproliferative Activity. FRONT CHEM. 2019, 7:92. DOI: 10.3389/fchem.2019.00092 IF 3.693

22. Mioc A; Mioc M ; Ghiulai R ; Voicu M ; Racoviceanu R ; Trandafirescu C; Dehelean C; Coricovac D; Soica C. Gold Nanoparticles as

Targeted Delivery Systems and Theranostic Agents in Cancer Therapy. CURRENT MEDICINAL CHEMISTRY, 2019, 26(35): 6493-6513.

DOI: 10.2174/0929867326666190506123721 IF 4.184

23. Muntean, D; Licker, M; Alexa, E; Popescu, I; Jianu, C; Buda, V; Dehelean, CA; Ghiulai, R; Horhat, F; Horhat, D; Danciu, C. Evaluation of

essential oil obtained from Menthaxpiperita L. against multidrug-resistant strains. INFECTION AND DRUG RESISTANCE, 2019, 12:2905-

2914, DOI: 10.2147/IDR.S218141 IF 2.984

24. Duca, A; Alexa, E; Dehelean, CA; Soica, C; Danciu, C; Popescu, I; Cocan, I; Lalescu, D; Muntean, DM. Assessment of Lipid Profile of

Eight Propolis Samples from Western Romania. FARMACIA, 2019, 67(1):126-132, DOI: 10.31925/farmacia.2019.1.17 IF 1.607

25. Nica D, Draghici G, Andrica FM, Popescu S, Coricovac D, Dehelean C* (autor coresp), Gergen I, Kovatsi L, Coleman M, Tsatsakis A.

Short-term effects of very low dose cadmium feeding on copper, manganese and iron homeostasis: A gastropod perspective.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2019, 65:9-13, DOI:10.1016/j.etap.2018.10.005 IF 3.292

26. Danciu, C; Muntean, D; Alexa, E; Farcas, C; Oprean, C; Zupko, I; Bor, A; Minda, D; Proks, M; Buda, V; Hancianu, M; Cioanca, O; Soica,

C; Popescu, S; Dehelean, CA. Phytochemical Characterization and Evaluation of the Antimicrobial, Antiproliferative and Pro-Apoptotic

Potential of Ephedra alata Decne. Hydroalcoholic Extract against the MCF-7 Breast Cancer Cell Line. MOLECULES, 2019, 24(1), Article

Number: 13, DOI: 10.3390/molecules24010013 IF 3.267

27. Danciu, C; Pinzaru, I; Coricovac, D; Andrica, F; Sizemore, I; Dehelean, C; Baderca, F; Lazureanu, V; Soica, C; Mioc, M; Radeke H. Betulin

silver nanoparticles qualify as efficient antimelanoma agents in in vitro and in vivo studies. EUROPEAN JOURNAL OF PHARMACEUTICS

AND BIOPHARMACEUTICS, 2019, 134:1–19, DOI: 10.1016/j.ejpb.2018.11.006 IF 4.604

28. Ursoniu, S; Sahebkar, A; Serban, MC; Pinzaru, I; Dehelean, C; Noveanu, L; Rysz, J; Banach, M. A systematic review and meta-analysis

of clinical trials investigating the effects of flaxseed supplementation on plasma C-reactive protein concentrations. ARCHIVES OF

MEDICAL SCIENCE, 2019, 15(1):12-22, DOI: 10.5114/aoms.2018.81034 IF 2.807

2018 1. Coricovac, D; Farcas, C; Nica, C; Pinzaru, I; Simu, S; Stoian, D; Soica, C; Proks, M; Avram, S; Navolan, D; Dumitru, C; Popovici, RA;

Dehelean, CA. Ethinylestradiol and Levonorgestrel as Active Agents in Normal Skin, and Pathological Conditions Induced by UVB

Exposure: In Vitro and In Ovo Assessments. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19(11):3600, DOI:

10.3390/ijms19113600 IF = 4.183

2. Danciu, C; Zupko, I; Bor, A; Schwiebs, A; Radeke, H; Hancianu, M; Cioanca, O; Alexa, E; Oprean, C; Bojin, F; Soica, C; Paunescu, V;

Dehelean, CA. Botanical Therapeutics: Phytochemical Screening and Biological Assessment of Chamomile, Parsley and Celery Extracts

against A375 Human Melanoma and Dendritic Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19(11):3624,

DOI: 10.3390/ijms19113624 IF = 4.183

3. Circioban, D; Ledeti, A; Vlase, G; Moaca, A; Ledeti, I; Farcas, C; Vlase, T; Dehelean, C. Thermal degradation, kinetic analysis and

evaluation of biological activity on human melanoma for artemisinin. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2018,

134(1):741-748, DOI: 10.1007/s10973-018-7497-z IF = 2.471

4. Circioban, D; Ledeti, I; Vlase, G; Ledeti, A; Axente, C; Vlase, T; Dehelean, C. Kinetics of heterogeneous-induced degradation for

artesunate and artemether. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2018, 134(1):749-756, DOI: 10.1007/s10973-

018-7257-0 IF = 2.471

5. Sturza, A; Pavel, I; Ancusa, S; Danciu, C; Dehelean, C; Duicu, O; Muntean, D. Quercetin exerts an inhibitory effect on cellular

bioenergetics of the B164A5 murine melanoma cell line. MOLECULAR AND CELLULAR BIOCHEMISTRY, 2018, 447(1-2):103-109, DOI:

10.1007/s11010-018-3296-x IF = 2.884

6. Mioc, M; Avram, S; Bercean, V; Kurunczi, L; Ghiulai, RM; Oprean, C; Coricovac, DE; Dehelean, C; Mioc, A; Balan-Porcarasu, M; Tatu,

C; Soica, C. Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as

Antiproliferative Agents in Colorectal Cancer. FRONTIERS IN CHEMISTRY, 2018, Article number 373, DOI: 10.3389/fchem.2018.00373

IF = 3.782

7. Cheverasan, A; Mioc, M; Simu, S; Soica, C; Dehelean, C; Szasz, F; Navolan, D; Poenaru, M. Binding Affinity of 17-beta-ethinylestradiol

to Normal and Mutant Types of Estrogen Receptors. REVISTA DE CHIMIE, 2018, 69(8):2067-2070 IF = 1.605

8. Coricovac, D; Dehelean, C; Moaca, EA; Pinzaru, I; Bratu, T; Navolan, D; Boruga, O. Cutaneous MelanomaA Long Road from Experimental

Models to Clinical Outcome: A Review. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19(6), Article number 1566,

DOI: 10.3390/ijms19061566 IF = 4.183

9. Mioc, M; Pavel, IZ; Ghiulai, R; Coricovac, DE; Farcas, C; Mihali, CV; Oprean, C; Serafim, V; Popovici, RA; Dehelean, CA; Shtilman, MI;

Tsatsakis, AM; Soica, C. The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma

Cells. FRONTIERS IN PHARMACOLOGY, 2018, Article number 429, DOI: 10.3389/fphar.2018.00429 IF = 3.845

10. Danciu, C; Pinzaru, IA; Dehelean, CA; Hancianu, M; Zupko, I; Navolan, D; Licker, M; Ghiulai, RM; Soica, CM. Antiproliferative and

antimicrobial properties of pure and encapsulated rutin. FARMACIA, 2018, 66(2):302-308 IF = 1.527

11. Falamas, A; Dehelean, CA; Pinzaru, SC. Monitoring of betulin nanoemulsion treatment and molecular changes in mouse skin cancer

using surface enhanced Raman spectroscopy. VIBRATIONAL SPECTROSCOPY, 2018, 95:45-50, DOI: 10.1016/j.vibspec.2018.01.004

IF = 1.861

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12. Cocan, I; Alexa, E; Danciu, C; Radulov, I; Galuscan, A; Obistioiu, D; Morvay, AA; Sumalan, RM; Poiana, MA; Pop, G; Dehelean, CA.

Phytochemical screening and biological activity of Lamiaceae family plant extracts. EXPERIMENTAL AND THERAPEUTIC MEDICINE,

2018, 15(2):1863-1870, DOI: 10.3892/etm.2017.5640 IF = 1.448

13. Bakonyi, M; Berko, S; Eros, G; Varju, G; Dehelean, CA; Budai-Szucs, M; Csanyi, E. A Review of Electroporation-based Antitumor Skin

Therapies and Investigation of Betulinic Acid-loaded Ointment. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18(5):693-

701, DOI: 10.2174/1871520617666171113120255 IF = 2.180

14. Pinzaru, I; Coricovac, D; Dehelean, C* (coresp autor); Moaca, EA; Mioc, M; Baderca, F; Sizemore, I; Brittle, S; Marti, D; Calina, CD;

Tsatsakis, AM; Soica, C. Stable PEG-coated silver nanoparticles - A comprehensive toxicological profile. FOOD AND CHEMICAL

TOXICOLOGY, 2018, 111:546-556, DOI: 10.1016/j.fct.2017.11.051 IF = 3.775

15. Alexa, E; Sumalan, RM; Danciu, C; Obistioiu, D; Negrea, M; Poiana, MA ; Rus, C; Radulov, I; Pop, G; Dehelean, C. Synergistic Antifungal,

Allelopatic and Anti-Proliferative Potential of Salvia officinalis L., and Thymus vulgaris L. Essential Oils. MOLECULES, 2018, 23(1), Article

number 185, DOI: 10.3390/molecules23010185 IF = 3.060

16. Belei, O; Olariu, L; Puiu, M; Jinca, C; Dehelean, C; Marcovici, T; Marginean, O. Continuous esomeprazole infusion versus bolus

administration and second look endoscopy for the prevention of rebleeding in children with a peptic ulcer. REVISTA ESPANOLA DE

ENFERMEDADES DIGESTIVAS, 2018, 110(6):352-357, DOI: 10.17235/reed.2018.4864/2017 IF = 1.858

17. Danciu, C; Soica, C; Antal, D; Alexa, E; Pavel, IZ; Ghiulai, R; Ardelean, F; Babuta, RM; Popescu, A; Dehelean, CA. Natural Compounds

in the Chemoprevention of Malignant Melanoma. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18(5):631-644, DOI:

10.2174/1871520617666171121142522 IF = 2.180

18. Moaca, EA; Farcas, C; Ghitu, A; Coricovac, D; Popovici, R; Caraba-Meita, NL; Ardelean, F; Antal, DS; Dehelean, C; Avram, S. A

Comparative Study of Melissa officinalis Leaves and Stems Ethanolic Extracts in terms of Antioxidant, Cytotoxic, and Antiproliferative

Potential. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, Article number 7860456, DOI:

10.1155/2018/7860456 IF = 1.984

19. Danciu, C; Avram, S; Pavel, IZ; Ghiulai, R; Dehelean, CA; Ersilia, A; Minda, D; Petrescu, C; Moaca, EA; Soica, C. Main Isoflavones Found

in Dietary Sources as Natural Anti-inflammatory Agents. CURRENT DRUG TARGETS, 2018, 19(7):841-853, DOI:

10.2174/1389450118666171109150731 IF = 2.642

20. Tanase, C; Domokos, E; Cosarca, S; Miklos, A; Imre, S; Domokos, J; Dehelean, CA. Study of the Ultrasound-assisted Extraction of

Polyphenols from Beech (Fagus sylvatica L.) Bark. BIORESOURCES, 2018, 13(2):2247-2267, DOI: 10.15376/biores.13.2.2247-2267 IF

= 1.396

21. Pinzaru, I; Heghes, A; Marti, D; Dehelean, C; Coricovac, D; Moaca, A; Moatar, M; Camen, D. Therapeutically Potential of Medicago sativa

Extracts Chemical and in vitro assessments. REVISTA DE CHIMIE, 2018, 69(1):121-124 IF = 1.605

22. Ledeti, A; Vlase, G; Vlase, T; Circioban, D; Dehelean, C; Ledeti, I. Kinetic study for solid-state degradation of mental disorder therapeutic

agents Amitriptyline, desipramine and imipramine. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2018, 131(1):155-165,

DOI: 10.1007/s10973-016-6064-8 IF = 2.471

23. Ledeti, A; Vlase, G; Vlase, T; Circioban, D; Dehelean, C; Ledeti, I; Suta, LM. Binary adduct formation of desipramine with dicarboxylic

acids An instrumental study. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2018, 131(1):167-173, DOI: 10.1007/s10973-

016-5967-8 IF = 2.471

24. Ledeti, I; Budiul, M; Matusz, P; Vlase, G; Circioban, D; Dehelean, C; Suta, LM; Caunii, A ; Ledeti, A; Vlase, T; Murariu, M; Bolintineanu,

S. Preformulation studies for nortriptyline Solid-state compatibility with pharmaceutical excipients. JOURNAL OF THERMAL ANALYSIS

AND CALORIMETRY, 2018, 131(1):191-199, DOI: 10.1007/s10973-017-6269-5 IF = 2.471

25. Alexa, E; Danciu, C; Radulov, I; Obistioiu, D; Sumalan, RM; Morar, A; Dehelean, CA. Phytochemical Screening and Biological Activity of

Menthax x piperita L. and Lavandula angustifolia Mill. Extracts. ANALYTICAL CELLULAR PATHOLOGY, 2018, Article Number: 2678924,

DOI: 10.1155/2018/2678924 IF = 1.788

2017 1. Caunii, A; Oprean, C; Cristea, M; Ivan, A; Danciu, C; Tatu, C; Paunescu, V; Marti, D; Tzanakakis, G; Spandidos, DA; Tsatsakis, A; Susan,

R; Soica, C; Avram, S; Dehelean, C. Effects of ursolic and oleanolic on SK-MEL-2 melanoma cells: In vitro and in vivo assays. International

Journal of Oncology, 2017, 51(6):1651-1660 IF = 3.333

2. Ungureanu, A; Zlatian, O; Mitroi, G; Drocas, A; Tirca, T; Calina, D; Dehelean, C; Docea, AO; Izotov, BN; Rakitskii, VN; Cioboata, R;

Spandidos, DA; Tsatsakis, AM; Gaman, A. Staphylococcus aureus colonisation in patients from a primary regional hospital. Molecular

Medicine Reports, 2017, 16(6):8771-8780, DOI: 10.3892/mmr.2017.7746 IF = 1.922

3. Ledeti, I; Bolintineanu, S; Vlase, G; Circioban, D; Dehelean, C; Suta, LM; Caunii, A; Ledeti, A; Vlase, T; Murariu, M. Evaluation of solid-

state thermal stability of donepezil in binary mixtures with excipients using instrumental techniques. Journal of Thermal Analysis and

Calorimetry, 2017, 130(1): 425-431, DOI: 10.1007/s10973-017-6250-3 IF = 2.209

4. Serafim, V; Shah, A; Puiu, M; Andreescu, N; Coricovac, D; Nosyrev, AE; Spandidos, DA; Tsatsakis, AM; Dehelean, C; Pinzaru, J.

Classification of cancer cell lines using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and statistical analysis.

International Journal of Molecular Medicine, 2017, 40(4):1096-1104, DOI: 10.3892/ijmm.2017.3083 IF = 2.784

5. Avram, S; Coricovac, DE; Pavel, IZ; Pinzaru, J; Ghiulai, R; Baderca, F; Soica, C; Muntean, D; Branisteanu, DE; Spandidos, DA; Tsatsakis,

AM; Dehelean, CA. Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude

mice. Oncology Reports, 2017, 38(1):89-99, DOI: 10.3892/or.2017.5658 IF = 2.976

6. Pavel, IZ; Iftode, OA; Pinzaru, I; Coricovac, D; Moaca, A; Farcas, C; Simu, SC; Soica, C; Dehelean, C; Motoc, A. Skin Specific Cells and

UVB Damage An experimental assessment. Revista de Chimie, 2017, 68(6):1229-1233 IF = 1.412

7. Pavel, IZ; Dehelean, CA; Farczadi, L; Muntean, DM; Vlase, L; Danciu, C; Csuk, R; Birsasteanu, F; Muntean, DM. Assessment of a Maslinic

Acid Derivative and its Metabolite in Rat Blood by Liquid Chromatography Coupled with Mass Spectrometry. Revista de Chimie, 2017,

68(5):1089-1094 IF = 1.412

8. Pavel, IZ; Parvu, AE; Dehelean, CA; Vlase, L; Csuk, R; Muntean, DM. Assessment of the antioxidant effect of a maslinic acid derivative

in an experimental model of acute inflammation. Farmacia, 2017, 65(3):390-395 IF = 1.507

9. Mioc, M; Soica, C; Bercean, V; Avram, S; Balan-Porcarasu, M; Coricovac, D; Ghiulai, R; Muntean, D; Andrica, F; Dehelean, C*(coresp

author); Spandidos, DA; Tsatsakis, AM; Kurunczi, L. Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-

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triazole derivatives with antibacterial and antiproliferative activity. International Journal of Oncology, 2017, 50(4):1175-1183, DOI:

10.3892/ijo.2017.3912 IF = 3.333

10. Coricovac, DE; Moaca, EA; Pinzaru, I; Citu, C; Soica, C; Mihali, CV; Pacurariu, C; Tutelyan, VA; Tsatsakis, A; Dehelean, CA.

Biocompatible Colloidal Suspensions Based on Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Toxicological Profile.

Frontiers in Pharmacology, 2017, Article Number: UNSP 154, DOI: 10.3389/fphar.2017.00154 IF = 3.831

11. Corina, D; Bojin, F; Ambrus, R; Muntean, D; Soica, C; Paunescu, V; Cristea, M; Pinzaru, I; Dehelean, C. Physico-chemical and Biological

Evaluation of Flavonols: Fisetin, Quercetin and Kaempferol Alone and Incorporated in beta Cyclodextrins. Anti-Cancer Agents in Medicinal

Chemistry, 2017, 17(4):615-626, DOI: 10.2174/1871520616666160621105306 IF = 2.556

12. Danciu, C; Pavel, IZ; Babuta, R; Ersilia, A; Suciu, O; Pop, G; Soica, C; Dehelean, C; Radulov, I. Total phenolic content, FTIR analysis,

and antiproliferative evaluation of lupin seeds harvest from western Romania. Annals of Agricultural and Environmental Medicine, 2017,

24(4):726-731, DOI: 10.26444/aaem/80795 IF = 1.116

13. Haidu, D; Parkanyi, D; Moldovan, RI; Savii, C; Pinzaru, I; Dehelean, C; Kurunczi, L. Elemental Characterization of Romanian Crop

Medicinal Plants by Neutron Activation Analysis. Journal of Analytical Methods in Chemistry, 2017, Article Number: 9748413, DOI:

10.1155/2017/9748413 IF = 1.262

14. Coricovac, DE; Dehelean, CA*(coresp autor); Cseh, L; Soica, CM; Boglut, A; Simu, GM. Evaluation of the impact induced by the

environmental exposure to a mixture of organic solvents on SKH1 mice. Farmacia, 2017, 65(1):125-131 IF = 1.507

2016 1. Trandafirescu, C; Borcan, F; Dehelean, C; Szabadai, Z; Nicolov, M; Soica, C. Study of the Interaction of Albendazole with Benzoic Acid.

I, Revista de Chimie, 2016, 67(11):2370-2374 IF = 1.232

2. Oprean, C; Zambori, C; Borcan, F; Soica, C; Zupko, I; Minorics, R; Bojin, F; Ambrus, R; Muntean, D; Danciu, C; Pinzaru, IA; Dehelean,

C; Paunescu, V; Tanasie, G. Anti-proliferative and antibacterial in vitro evaluation of the polyurethane nanostructures incorporating

pentacyclic triterpenes. Pharmaceutical Biology, 2016, 54(11):2714-2722, DOI: 10.1080/13880209.2016.1180538 IF = 1.916

3. Oprean, C; Mioc, M; Csanyi, E; Ambrus, R; Bojin, F; Tatu, C; Cristea, M; Ivan, A; Danciu, C; Dehelean, C; Paunescu, V; Soica, C.

Improvement of ursolic and oleanolic acids' antitumor activity by complexation with hydrophilic cyclodextrins. Biomedicine &

Pharmacotherapy, 2016, 83:1095-1104, DOI: 10.1016/j.biopha.2016.08.030 IF = 2.759

4. Oprean, C; Borcan, F; Pavel, I; Dema, A; Danciu, C; Soica, C; Dehelean, C; Nicu, A; Ardelean, A; Cristea, M; Ivan, A; Tatu, C; Bojin, F.

In Vivo Biological Evaluation of Polyurethane Nanostructures with Ursolic and Oleanolic Acids on Chemically-induced Skin

Carcinogenesis. In Vivo, 2016, 30(5):633-638 IF = 0.953

5. Dehelean, CA; Soica, C; Pinzaru, I; Coricovac, D; Danciu, C; Pavel, I; Borcan, F; Spandidos, DA; Tsatsakis, AM; Baderca, F. Sex

differences and pathology status correlated to the toxicity of some common carcinogens in experimental skin carcinoma. Food and

Chemical Toxicology, 2016, 95:149-158, DOI: 10.1016/j.fct.2016.07.007 IF = 3.778

6. Antal, DS; Pinzaru, I; Borcan, F; Marti, TD; Ledeti, I; Coricovac, D; Schwaiger, S; Stuppner, H; Dehelean, CA*(coresp author); Ollivier,

E; Soica, C. Inclusion Complexes of the Aurone Sulfuretin and the Chalcone Butein from Cotinus coggygria Wood in Two Cyclodextrin

Types First data on physico-chemical properties. Revista de Chimie, 2016, 67(6):1104-1109 IF = 1.232

7. Trandafirescu, C; Ledeti, I; Coricovac, DE; Soica, CM; Pinzaru, I; Dehelean, CA; Iacob, RE; Borcan, F. Optimization of Hollow Aliphatic

Polyurethane Particles Used as a Drug Delivery System. Materiale Plastice, 2016, 53(2):205-210 IF = 0.778

8. Trandafirescu, C; Soica, C; Ledeti, A; Borcan, F; Suta, LM; Murariu, M; Dehelean, C; Ionescu, D; Ledeti, I. Preformulation Studies for

Albendazole A DSC and FTIR analysis of binary mixtures with excipients. Revista de Chimie, 2016, 67(3):463-467 IF = 1.232

9. Popovici, RA; Rusu, LC; Podariu, AC; Motoc, O; Motoc, V; Dehelean, C; Pinzaru, I. The in vitro Effects of Several Products of Dental Use

on Tumor Cell Lines. Revista de Chimie, 2016, 67(3):517-519 IF = 1.232

10. Ledeti, I; Vlase, G; Vlase, T; Murariu, M; Trandafirescu, C; Soica, C; Suta, LM; Dehelean, C; Ledeti, A. Non-isothermal Isoconversional

Kinetic Study Regarding the Degradation of Albendazole. Revista de Chimie, 2016, 67(3):549-552 IF = 1.232

11. Andrica, FM; Draghici, GA; Soica, C; Pinzaru, I; Coricovac, D; Citu, C; Dehelean, C. Antioxidant Activity Assessment of Ethanolic Spirulina

Extracts. Revista de Chimie, 2016, 67(2):289-290 IF = 1.232

12. Simu, GM; Coricovac, D; Cseh, L; Soica, C; Borcan, F; Ionescu, D; Andoni, M; Dragos, D; Dehelean, C. Assessment of Skin Injuries

Induced by Organic and Inorganic Phases of the Cosorb Process by Means of Non-invasives Techniques. Revista de Chimie, 2016,

67(2):291-296 IF = 1.232

13. Ledeti, A; Vlase, G; Ledeti, I; Vlase, T; Matusz, P; Dehelean, C; Circioban, D; Stelea, L; Suta, LM. Thermal Stability of Desipramine and

Imipramine. Revista de Chimie, 2016, 67(2):336-338 IF = 1.232

14. Vlaia, LL; Vlaia, V; Olariu, IV; Mut, AM; Gafitanu, CA; Dehelean, C; Navolan, D; Lupuleasa, D; Coneac, GH. Preparation and

Characterization of Inclusions Complexes Between Propolis Ethanolic Extracts and 2-hydroxypropyl-beta-cyclodextrin. Revista de Chimie,

2016, 67(2):378-381 IF = 1.232

15. Avram, S; Danciu, C; Pavel, IZ; Ceausu, RA; Avram, S; Dehelean, C; Raica, M. Polyphenols, Antioxidant Activity and Anti-angiogenic

Potential of Red and White Grapes. Revista de Chimie, 2016, 67(2):382-385 IF = 1.232

16. Andor, B; Danciu, C; Alexa, E; Zupko, I; Hogea, E; Cioca, A; Coricovac, D; Pinzaru, I; Patrascu, J; Mioc, M; Cristina, RT; Soica, C;

Dehelean, C. Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In

Vitro and In Vivo Evaluations. Evidence-Based Complementary and Alternative Medicine, 2016, Article Number: 7638542, DOI:

10.1155/2016/7638542 IF = 1.74

17. Pavel, IZ; Danciu, C; Oprean, C; Dehelean, CA; Muntean, D; Csuk, R; Muntean, DM. In Vitro Evaluation of the Antimicrobial Ability and

Cytotoxicity on Two Melanoma Cell Lines of a Benzylamide Derivative of Maslinic Acid. Analytical Cellular Pathology, 2016, Article

Number: 2787623, DOI: 10.1155/2016/2787623 IF = 1.078

18. Soica, C; Coricovac, D; Dehelean, C*(coresp); Pinzaru, I; Mioc, M; Danciu, C; Fulias,; Puiu, M; Sitaru, C. Nanocarriers as Tools in

Delivering Active Compounds for Immune System Related Pathologies. Recent Patents on Nanotechnology, 2016, 10(2):128-145, DOI:

10.2174/1872210510999160427113345 IF = 0.912

19. Vlad, DC; Popescu, R; Dumitrascu, V; Cimporescu, A; Vlad, CS; Vagvolgyi, C; Krisch, J; Dehelean, C; Horhat, FG. Phytocomponents

identification in Mistletoe (Viscum album) young leaves and branches, by GC-MS and antiproliferative effect on HEPG2 and MCF7 cell

lines. Farmacia, 2016, 64(1):82-87 IF = 1.348

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20. Avram, S; Avram, S; Dehelean, C. Effective Predictor of Human Mast Cell Tryptase Inhibitors. Revista de Chimie, 2016, 67(1):119-122 IF

= 1.232

21. Balazs, B; Sipos, P; Danciu, C; Avram, S; Soica, C; Dehelean, C; Varju, G; Eros, G; Budai-Szucs, M; Berko, S; Csanyi, E. ATR-FTIR and

Raman spectroscopic investigation of the electroporation-mediated transdermal delivery of a nanocarrier system containing an antitumour

drug. Biomedical Optics Express, 2016, 7(1):67-78, DOI: 10.1364/BOE.7.000067 IF = 3.337

2015 1. Circioban, D; Dehelean, C; Suta, LM; Murariu, M; Vlase, G; Nita, L; Soica, C; Fulias, A. Synthesis and Physico-chemical Characterization

of Theophylline-succinic Acid Binary Adduct. Revista de Chimie, 2015, 66(12):1982-1985 IF = 0.956

2. Andoni, M; Patrascu, JM; Dehelean, CA; Simu, GM; Soica, C; Antal, D; Pop, R. Comparisons Between Tridentate Bis(benzazoles)-

pyridine and Bis(benzazoles)triazine Ligands: a Theoretical Study. Croatica Chemica Acta, 2015, 88(3):241, DOI: 10.5562/cca2647 IF =

0.732

3. Ledeti, I; Avram, S; Bercean, V; Vlase, G; Vlase, T; Ledeti, A; Zupko, I; Mioc, M; Suta, LM; Soica, C; Dehelean, C. Solid-State

Characterization and Biological Activity of Betulonic Acid Derivatives. Molecules, 2015, 20(12):22691-22702, DOI:

10.3390/molecules201219876 IF = 2.465

4. Pavel, IZ; Duicu, OM; Danciu, C; Dehelean, C; Bojin, FM; Paunescu, V; Muntean, DM; Sturza, A; Noveanu, L. Immune and Bioenergetic

Profiling of a Human Dermal Fibroblast Cell Line. Revista de Chimie, 2015, 66(11):1755-1758 IF = 0.956

5. Coricovac, D; Soica, C; Muntean, D; Popovici, RA; Dehelean, CA; Hogea, E. Assessment of the Effects Induced by Two Triterpenoids on

Liver Mitochondria Respiratory Function Isolated from Aged Rats. Revista de Chimie, 2015, 66(10):1707-1710 IF = 0.956

6. Danciu, C; Berko, S; Varju, G; Balazs, B; Kemeny, L; Nemeth, IB; Cioca, A; Petrus, A; Dehelean, C; Cosmin, CI; Amaricai, E; Toma, CC.

The Effect of Electroporation of a Lyotroic Liquid Crystal Genistein-Based Formulation in the Recovery of Murine Melanoma Lesions.

International Journal of Molecular Sciences, 2015, 16(7):15425-15441, DOI: 10.3390/ijms160715425 IF = 3.257

7. Antal, DS; Citu, C; Ardelean, F; Dehelean, C*(coresp author); Vlaia, L; Soica, C; Vlaia, V; Biris, M; Sas, I. Metallome of Origanum vulgare:

the unknown side of a medicinal and aromatic plant used worldwide. Farmacia, 2015, 63(4):534-538 IF = 1.162

8. Hepcal, IC; Toma, CC; Olah, N; Dehelean, C; Motoc, A; Ardelean, S; Conea, S; Morgovan, C. Study of the oral contraceptives' use by

women from Western Romania. Farmacia, 2015, 63(4):607-612 IF = 1.162

9. Grigoriu, IC; Cioroiu, BI; Strugaru, AM; Agoroaei, L; Dehelean, C; Stoian, D; Butnaru, E. Preliminary Impurity Profile Study of Desloratadine

Used in Toxicological Studies. Revista de Chimie, 2015, 66(7):1064-1067 IF = 0.956

10. Danciu, C; Borcan, F; Soica, C; Zupko, I; Csanyi, E; Ambrus, R; Muntean, D; Sass, C; Antal, D; Toma, C; Dehelean, C. Polyurethane

Microstructures-a Good or Bad in vitro Partner for the Isoflavone Genistein? Natural Product Communications, 2015, 10(6):951-954 IF =

0.884

11. Andoni, M; Pop, R; Soica, C; Simu, GM; Ilici, M; Ardelean, S; Onisei, D; Dehelean, CA. Theoretical Study Regarding the Reactivity of 5-

nitrofuran-2-carboxaldehyde Thiosemicarbazone. Revista de Chimie, 2015, 66(5):637-639 IF = 0.956

12. Danciu, C; Oprean, C; Coricovac, DE; Andreea, C; Cimpean, A; Radeke, H; Soica, C; Dehelean, C. Behaviour of four different B16 murine

melanoma cell sublines: C57BL/6J skin. International Journal of Experimental Pathology, 2015, 96(2):73-80, DOI: 10.1111/iep.12114 IF

= 2.125

13. Heghes, A; Hadaruga, NG; Fulias, AV; Bandur, GN; Hadaruga, DI; Dehelean, CA. Capsicum annuum extracts/beta-cyclodextrin

complexes Thermal analyses-Karl Fischer water titration correlations and antioxidant activity. Journal of Thermal Analysis and Calorimetry,

2015, 120(1):603-615, DOI: 10.1007/s10973-014-4229-x IF = 1.781

14. Pfarr, K; Danciu, C; Arlt, O; Neske, C; Dehelean, C; Pfeilschifter, JM; Radeke, HH. Simultaneous and Dose Dependent Melanoma

Cytotoxic and Immune Stimulatory Activity of Betulin. Plos One, 2015, 10(3), Article Number: UNSP e0118802, DOI:

10.1371/journal.pone.0118802 IF = 3.057

15. Antal, DS; Vlaia, V; Dehelean, CA; Vlaia, L; Trandafirescu, C; Ardelean, F; Pinzaru, I; Ionescu, D. Zinc Across Medicinal Plants from

Romanian Biodiversity and the Implications for Human Health. Revista de Chimie, 2015, 66(2):236-239 IF = 0.956

16. Danciu, C; Vlaia, L; Fetea, F; Hancianu, M; Coricovac, DE; Ciurlea, SA; Soica, CM; Marincu, I; Vlaia, V; Dehelean, CA; Trandafirescu, C.

Evaluation of phenolic profile, antioxidant and anticancer potential of two main representants of Zingiberaceae family against B164A5

murine melanoma cells. Biological Research, 2015, 48, Article number 1, DOI: 10.1186/0717-6287-48-1 IF = 1.328

17. Danciu, C; Soica, C; Dehelean, C*(coresp author); Zupko, I; Csanyi, E; Pinzaru, I. Preliminary In Vitro Evaluation of Genistein

Chemopreventive Capacity as a Result of Esterification and Cyclodextrin Encapsulation. Analytical Cellular Pathology, 2015, Article

Number: 262930, DOI: 10.1155/2015/262930 IF = 0.459

18. Ledeti, I; Bercean, V; Alexa, A; Soica, C; Suta, LM; Dehelean, C; Trandafirescu, C; Muntean, D; Licker, M; Fulias, A. Preparation and

Antibacterial Properties of Substituted 1,2,4-Triazoles. Journal of Chemistry, 2015, Article Number: 879343, DOI: 10.1155/2015/879343

IF = 0.996

19. Citu, IM; Coricovac, D; Kerti, V; Duicu, O; Privistirescu, A; Ardelean, S; Muntean, D; Dehelean, C. Decreased respiratory function in liver

mitochondria isolated from healty old rats. Farmacia, 2015, 63(1):99-103 IF = 1.162

2014 1. Trandafirescu, C; Avram, S; Soica, C; Aigner, Z; Arpad, G; Kata, M; Dehelean, C; Szabadai, Z; Borcan, F. Solid-state Characterization of

Bifonazole - beta-cyclodextrin Binary Systems. Revista de Chimie, 2014, 65(11):1336-1339 IF = 0.81

2. Soica, C; Fulias, A; Vlase, G; Dehelean, C; Vlase, T; Ledeti, I. Synthesis and thermal behavior of new ambazone complexes with some

transitional cations. Journal of Thermal Analysis and Calorimetry, 2014, 118(2):1305-1311, DOI: 10.1007/s10973-014-3858-4 IF = 2.042

3. Trandafirescu, C; Antal, D; Soica, C; Zupko, I; Minorics, R; Ambrus, R; Borcan, F; Oprean, C; Danciu, C; Avram, S; Dehelean, C; Nita, S;

Vlaia, L. Cyclodextrin Complexes of Oleanolic and Ursolic Acid Physico-chemical and biological preliminary evaluation. Revista de Chimie,

2014, 65(10):1163-1167 IF = 0.81

4. Danciu, C; Coricovac, DE; Soica, C; Dumitrascu, V; Simu, G; Antal, D; Lajos, K; Dehelean, CA; Borcan, F. Evaluation of Skin Physiological

Parameters in SKH1 Mice Experimental Model after Exposure to Aggressive Factors like UVB using Non-invasive Methods. Revista de

Chimie, 2014, 65(10):1195-1199 IF = 0.81

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5. Duicu, O; Ciurlea, S; Dehelean, C; Ardelean, S; Andrica, F; Muntean, D; Soica, C; Antal, D; Coricovac, D; Pinzaru, I. Analysis of a Betulinic

Acid Formulation on Liver Mitochondria Isolated from Mice with Induced Murine Melanoma. Revista de Chimie, 2014, 65(8):956-959 IF =

0.81

6. Chicu, SA; Munteanu, M; Citu, I; Soica, C; Dehelean, C; Trandafirescu, C; Funar-Timofei, S; Ionescu, D; Simu, GM. The Hydractinia

echinata Test-System. III: Structure-Toxicity Relationship Study of Some Azo-, Azo-Anilide, and Diazonium Salt Derivatives. Molecules,

2014, 19(7):9798-9817, DOI: 10.3390/molecules19079798 IF = 2.416

7. Soica, C; Danciu, C; Savoiu-Balint, G; Borcan, F; Ambrus, R; Zupko, I; Bojin, F; Coricovac, D; Ciurlea, S; Avram, S; Dehelean, CA; Olariu,

T; Matusz, P. Betulinic Acid in Complex with a Gamma-Cyclodextrin Derivative Decreases Proliferation and in Vivo Tumor Development

of Non-Metastatic and Metastatic B164A5 Cells. International Journal of Molecular Sciences, 2014, 15(5):8235-8255, DOI:

10.3390/ijms15058235 IF = 2.862

8. Coricovac, D; Dobrea, C; Dehelean, C; Duicu, O; Noveanu, L; Muntean, D; Lighezan, R. The Effects of Glycyrrhiza Glabra L. Total Extract

on Liver Mitochondrial Respiratory Function. Revista de Chimie, 2014, 65(5):608-611 IF = 0.81

9. Kerti, V; Coricovac, D; Duicu, O; Danila, M; Dehelean, C; Fagadar-Cosma, E; Muntean, D; Noveanu, L. Modulation of Respiratory Function

by 5,10,15,20-Tetrakis(N-methyl-4-pyridyl)Porphyrin-Zn(II) Tetrachloride in Isolated Rat Liver Mitochondria. Revista de Chimie, 2014,

65(4):447-449 IF = 0.81

10. Soica, C; Oprean, C; Borcan, F; Danciu, C; Trandafirescu, C; Coricovac, D; Crainiceanu, Z; Dehelean, CA; Munteanu, M. The Synergistic

Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-gamma-Cyclodextrin. Molecules, 2014, 19(4):4924-4940,

DOI: 10.3390/molecules19044924 IF = 2.416

11. Danciu, C; Soica, C; Oltean, M; Avram, S; Borcan, F; Csanyi, E; Ambrus, R; Zupko, I; Muntean, D; Dehelean, CA; Craina, M; Popovici,

RA. Genistein in 1: 1 Inclusion Complexes with Ramified Cyclodextrins: Theoretical, Physicochemical and Biological Evaluation.

International Journal of Molecular Sciences, 2014, 15(2):1962-1982, DOI: 10.3390/ijms15021962 IF = 2.862

12. Soica, C; Trandafirescu, C; Danciu, C; Muntean, D; Dehelean, C; Simu, G. New Improved Drug Delivery Technologies for Pentacyclic

Triterpenes: A Review. Protein and Peptide Letters, 2014, 21 (11):1137-1145, DOI: 10.2174/0929866521666140807115109 IF = 1.068

13. Gheorgheosu, D; Duicu, O; Dehelean, C, Soica, C; Muntean, D. Betulinic Acid as a Potent and Complex Antitumor Phytochemical: A

Minireview. Anti-Cancer Agents in Medicinal Chemistry, 2014, 14(7):936-945, DOI: 10.2174/1871520614666140223192148 IF = 2.469

2013 1. Cinta-Pinzaru S, Falamas A, Dehelean C, Morari C, Venter M. Double Amino-Functionalised Ag Nanoparticles as SERS tags in Raman

diagnostic. Croat Chem Acta. 2013, 86(3):233-244, ISSN: 0011-1643 IF = 0.556

2. Danciu, C; Falamas, A; Dehelean, C*(coresp author); Soica, C; Radeke, H; Barbu-Tudoran, L; Bojin, F; Pinzaru, SC; Munteanu, MF. A

characterization of four B16 murine melanoma cell sublines molecular fingerprint and proliferation behavior. Cancer Cell International,

2013, 13, Article Number: 75, DOI: 10.1186/1475-2867-13-75 IF = 1.989

3. Alexa E, Dehelean CA, Poiana MA, Radulov I, Cimpean MA, Bordean DM, Tulcan C, Pop G. The occurence of mycotoxins in wheat from

western Romania and histopathological impact as effect of feed intake. Chem Cent J. 2013, 7:99, DOI:10.1186/1752-153X-7-99 IF = 1.663

4. Gheorgheosu D, Jung M, Schmid T, Oren B, Dehelean C, Muntean D, Brüne B. Betulinic acid suppresses NGAL-inducedepithelial-to-

mesenchymaltransition in melanoma. Biol Chem. 2013, 394(6):773-781, ISSN 1437-4315 IF = 2.689

5. Dehelean CA; Feflea S; Gheorgheosu D; Ganta S; Cimpean AM; Muntean D; Amiji MM. Anti-angiogenic and anti-cancer evaluation of

betulin nanoemulsion in chicken chorioallantoic membrane and skin carcinoma in Balb/c mice. J Biomed Nanotechnol. 2013, 9(4):577-

589, ISSN 1550-7033, IF=7.578

6. Cinta-Pinzaru S, Falamas A, Dehelean CA. Molecular conformation changes along the malignancy revealed by optical nanosensors. J

Cell Mol Med. 2013, 17(2):277-286, ISSN 1582-4934 IF = 3.698

7. Danciu C, Borcan F, Bojin F, Zupko I, Dehelean C. Effect of the Isoflavone Genistein on Tumor Size, Metastasis Potential and Melanization

in a B16 Mouse Model of Murine Melanoma. Nat Prod Commun. 2013, 8(3):343-346, ISSN 1934-578X IF=0.924

2012 1. Dehelean, CA; Soica, C; Ledeti, I; Aluas, M; Zupko, I; Galuscan, A; Cinta-Pinzaru, S; Munteanu, M. Study of the betulin enriched birch

bark extracts effects on human carcinoma cells and ear inflammation. Chemistry Central Journal, Article number 137, 2012. DOI:

10.1186/1752-153X-6-137 IF = 1.312

2. Soica C, Dehelean CA*(coresp author), Danciu C, Wang HM, Wenz G, Ambrus R, Bojin FM. Betulin Complex in γ-Cyclodextrin

Derivatives: Properties and Antineoplasic Activities in In Vitro and In Vivo Tumor Models. Int J Mol Sci. 2012, 13(11):14992-15011, ISSN

1422-0067 IF = 2.464

3. Borcan F, Soica CM, Dehelean CA, Ganta S, Amiji MM. Size and Stability Optimization for Polyurethane Nanostructures used as

Transdermal Drug Vehicle. Rev Chim. 2012, 63(11):1164-1166, 0034-7752, IF = 0.538

4. Borcan F, Soica CM, Ganta S, Amiji MM, Dehelean CA, Munteanu MF. Synthesis and preliminary in vivo evaluations of polyurethane

microstructures for transdermal drug delivery. Chem Cent J. 2012, 6(87), DOI: 10.1186/1752-153X-6-87, ISSN 1752-153X IF= 1.312

5. Dehelean CA, Feflea S, Molnar J, Zupko I, Soica C. Betulin as an Antitumor Agent Tested in vitro on A431, HeLa and MCF7, and as an

Angiogenic Inhibitor in vivo in the CAM Assay. Nat Prod Commun. 2012, 7(8):981-985, ISSN 1934-578X IF=0.956

6. Cinta-Pinzaru S, Dehelean CA*(coresp author), Soica C, Culea M, Borcan F. Evaluation and differentiation of the Betulaceae birch bark

species and their bioactive triterpene content using analytical FT-vibrational spectroscopy and GC-MS. Chem Cent J. 2012, 6(67), DOI:

10.1186/1752-153X-6-67, ISSN 1752-153X IF= 1.312

7. Danciu C, Soica C, Csanyi E, Ambrus R, Feflea S, Peev C, Dehelean C. Changes in the anti-inflammatory activity of soy isoflavonoid

genistein versus genistein incorporated in two types of cyclodextrin derivatives. Chem Cent J. 2012, 6(58), DOI: 10.1186/1752-153X-6-

58, ISSN 1752-153X IF= 1.312

8. Ciurlea S, Dehelean CA*(coresp author), Cinta-Pinzaru S, Falamas A, Muresan A, Loghin F. Raman spectroscopy investigations of the

CD1Nu/Nu mouse skin precarcinoma damages. Farmacia, 2012, 60(3):448-456, ISSN 0014-8237 IF = 0.578

9. Soica C, Dehelean C, Peev C, Aluas M, Zupko I, Kasa Peter, Alexa E. Physico-chemical comparison study of betulinic acid, betulin and

birch bark extract and in vitro investigation of their cytotoxic effects towards skin epidermoid carcinoma (A431), breast carcinoma (MCF7)

and cervix adenocarcinoma (HeLa) cell-lines. Nat Prod Res. 2012, 26(10):968-974, ISSN 1478-6419 IF = 1.031

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2011 1. Dehelean CA, Feflea S, Ganta S, Amiji M. Anti-Angiogenic Effects of Betulinic Acid Administered in Nanoemulsion Formulation using

Chorioallantoic Membrane Assay. J Biomed Nanotechnol. 2011, 7(2):317-324, ISSN 1550-7033 IF= 4.216

2. Tanasie, G; Bojin, F; Ordodi, V; Gruia, A; Gavriliuc, O; Cristea, M; Galuscan, A; Dehelean, C; Vintila, R; Tatu, C; Panaitescu, CB;

Paunescu, V. Epithelization of skin lesions in animal model treated with mesenchymal stem cells and derivatives. Romanian

Biotechnological Letters, 2011, 16(2):6072-6079 IF = 0.349

3. Falamas, A; Dehelean, C; Pinzaru, SC. Raman and SERS characterization of normal pathological skin. Studia Universitatis Babes-Bolyai

Chemia, 2011, 56(4):89-96 IF = 0.129

4. Borza C, Oancea C, Mateescu R, Balint-Savoiu G, Cristescu C, Andoni M, Simu GM, Butur M, Dehelean C, Pauncu EA. Evaluation of the

environmental and work risk factors in building-workers. J Food Agric Environ, Section Health, 2011, 9(1):175-176, ISSN 1459-0255 IF =

0.517

5. Dehelean CA, Soica C, Peev C, Ciurlea S, Feflea S, P. Kasa jr. A pharmaco-toxicological evaluation for betulinic acid mixed with

hydroxipropilgamma cyclodextrin on in vitro and in vivo models. Farmacia, 59(1):51-59, 2011, ISSN 0014-8237 IF= 0.669

6. Falamas A, Pinzaru S, Dehelean C, Peev C, Soica C, Betulin and its natural resource as potential anticancer drug candidate seen by FT-

Raman and FT-IR spectroscopy. J Raman Spectrosc, 2011, 42 (1):97-107, DOI:10.1002/jrs.2658, ISSN 0377-0486 IF = 3.087

7. Tiulea C, Peev C, Brezovan D, Dehelean C, Motoc A, A comparison regarding antiproliferative action between soy total extract and

genistein. Rom J Morphol Embryo, 2011, 52(3 suppl):1065-1069, ISSN 1220-0522 IF = 0.523

2010 1. Profire L, Cojocariu A, Oprea AM, Lupusoru CE, Ghiciuc CM, Dehelean CA, Vasile C. Synthesis and Characterization of New Nitric Oxide

Donor Compounds Based on Theophylline and Paracetamol. Rev Chim. 2010, 61(12):1150-1154, ISSN:0034-7752 IF = 0.693

2. Soica, CM; Peev, CI; Ciurlea, S; Ambrus, R; Dehelean, C. Physico-chemical and toxicological evaluations of betulin and betulinic acid

interactions with hydrophilic cyclodextrins. Farmacia, 2010, 58(5):611-619 IF = 0.850

3. Szuts, A; Budai-Szucs, M; Soica, C; Dehelean, CA; Szabo-Revesz, P. Evaluation of the interaction between a sucrose ester and

diclofenac sodium. Farmacia, 2010, 58(2):211-217 IF = 0.850

4. Falamas A, Cinta Pinzaru S, Dehelean CA, Venter MM, Raman Imaging of In Vivo Damaged Skin Tissues from Mice Specimens. Stud

Univ Babes Bol, Seria Chemia, 2010, 2:273-283, ISSN 1224-7154 IF = 0.231

2009 1. Antal DS, Dehelean CA, Peev CI, Anke M. Rubidium in medicinal Plants contribution to the research of a potentially essential element.

Rev Chim. 2009, 60(2):156-159, ISSN:0034-7752 IF = 0.552

2008 1. Dehelean CA, Şoica C, Peev C, Gruia AT, Seclaman E. Physico-chemical and molecular analysis of antitumoral pentacyclic triterpenes

in complexation with gamma-cyclodextrin. Rev Chim. 2008, 59(8):887-890, ISSN 0034-7752 IF = 0.389

2. Şoica C, Dehelean CA, Ordodi V, Antal D, Vlaia V. Complexation with hydroxipropilgamma cyclodextrin of birch tree extract. Physico-

chemical characterisation of their binary products. Rev Chim. 2008, 59(6):678-681, ISSN 0034-7752 IF = 0.389

2007 1. Aluaş M, Şoica C, Gyeresi A, Dehelean C, Simion S. Physico-chemical analysis of binary complexes of furosemide and randomly

methylated beta cyclodextrin, Rev Chim. 2007, 58(10):892-896, ISSN 0034-7752 IF = 0.261

2. Şoica C, Gyeresi A, Frentiu B, Dehelean CA, Aluas M. Preparation and physico-chemical characterization of chlorthalidone-

hydroxypropyl-β-cyclodextrin binary systems. Rev Chim. 2007, 58(7):606-611, ISSN 0034-7752 IF = 0.261

3. Peev CI, Vlase L, Antal DS, Dehelean CA, Szabadai Z. Determination of some polyphenolic compounds in buds of Alnus and Corylus

species by HPLC. Chem Nat Compd. 2007, 43(3):259-262, ISSN 0009-3130 IF = 0.442

4. Ambrus R, Aigner Z, Dehelean C, Şoica C, Revesz P. Physico-chemical studies on solid dispersion of niflumic acid prepared with PVP.

Rev Chim. 2007, 58(1):60-64, ISSN 0034-7752 IF = 0.261

ISI PROCEEDINGS – WEB OF SCIENCE 1. Circioban, D; Ledeti, A; Vlase, G; Coricovac, D; Moaca, A; Farcas, C; Vlase, T; Ledeti, I; Dehelean, C. Guest-host interactions and

complex formation for artemisinin with cyclodextrins: instrumental analysis and evaluation of biological activity. JOURNAL OF THERMAL

ANALYSIS AND CALORIMETRY, 2018, 134(2):1375-1384, Proceedings Paper IF = 2.471

2. Fulias, A; Ledeti, I; Vlase, G; Vlase, T; Soica, C; Dehelean, C; Oprean, C; Bojin, F; Suta, LM; Bercean, V; Avram, S. Thermal degradation,

kinetic analysis, and apoptosis induction in human melanoma for oleanolic and ursolic acids. JOURNAL OF THERMAL ANALYSIS AND

CALORIMETRY, 2016, 125(2):759-768, DOI: 10.1007/s10973-015-5052-8 IF = 1.953

3. Falamas, A; Pinzaru, SC; Chis, V; Dehelean, C. Spectroscopic investigations of newly formed betulin-cyclodextrin guest-host type

complexes as potential anti skin cancer candidates. JOURNAL OF MOLECULAR STRUCTURE, 2011, 993(1-3):297-301, Special Issue:

SI, DOI: 10.1016/j.molstruc.2010.11.044 IF = 1.634

4. Pinzaru, SC; Dehelean, CA; Falamas, A; Leopold, N; Lehene, C. Cancer tissue screening using Surface Enhanced Raman Scattering.

LASER APPLICATIONS IN LIFE SCIENCES, 2010, Edited by: Kinnunen, M; Myllyla, R, Book Series: Proceedings of SPIE, Volume: 7376,

Article Number: UNSP 73760T, DOI: 10.1117/12.871378 IF = 0.694

5. Peev, C; Vlase, L; Dehelean, C; Soica, C; Feflea, S; Alexa, E. HPLC comparative analysis of polyphenolic content of propolis and black

poplar foliar bud extracts. ACTUAL TASKS ON AGRICULTURAL ENGINEERING, PROCEEDINGS, 2009, Edited by: Kosutic, S, Book

Series: Actual Tasks on Agricultural Engineering-Zagreb, Volume: 37:Pages: 395-+ IF = -

6. Dehelean, CA; Pinzaru, SC; Peev, CI; Soica, C; Antal, DS. Characterization of birch tree leaves, buds and bark dry extracts with antitumor

activity. JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 2007, 9(3):783-787, Special Issue: SI, Proceedings Paper

IF = 0.827

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Curriculum vitae

19

PRINCIPALELE BREVETE ȘI PROPUNERI DE BREVET / PATENTS

1. Jumanca D, Galuscan A, Florita S, Podariu A, Florita Z, Dehelean C, Borcan F. Compoziție pentru pastă de dinți (Composition for toothpaste), Patent no 127805, OSIM / 28.II.2014

2. Jumanca D, Gălușcan A, Borcan F, Florița S, Dehelean C, Florița Z. Procedeu și dispozitiv pentru producerea nanogelurilor și microgelurilor pe bază de silicați alcalino-pământoși (Procedure and device for producing nanogels and microgels based on alcalino-grand silicates), Patent no 128480, OSIM / 26.II.2016

3. Pop G, Alexa E, Imbre I, Palicica R, Dehelean C, Danciu C, Andrica F. Unguent antibacterian pe bază de extract de măghiran (Origanum majorana L.) şi scoarţă de mesteacăn (Betula pendula Roth.), Registry office OMIS A/01015/17.12.2015, published in the Official Industrial Property Bulletin, Section Brevete de Inventie, No.6, 2016

4. Borcan LC, Popescu FG, Borcan F, Păuncu EA, Tomescu MC, Dehelean CA. Produs absorbant pentru hidrogen sulfurat şi procedeu de obţinere a acestuia / Absorbent product for hydrogen sulphide and process for obtaining it. CBI A/00040 from 25.01.2019

CAPITOLE DE CARTE / BOOK CHAPTERS (INTERNATIONAL ED.)

1. Simona Cîntă Pînzaru, A. Fălămaș, C.A. Dehelean. Chapter 6 - Raman Spectroscopy: A Key Analytical Tool for New Drugs Research and Development. Studies in Natural Products Chemistry Volume 61, 2018, Pages 211-250. DOI: 10.1016/B978-0-444-64183-0.00006-3, ISBN: 978-0-444-64183-0, ISSN: 1572-5995, Elsevier 2019

2. Codruta Soica, Iulia Pinzaru, Cristina Trandafirescu, Florina Andrica, Corina Danciu, Marius Mioc, Dorina Coricovac, Cassian Sitaru, Cristina Dehelean. Chapter 5 - Silver-, gold-, and iron-based metallic nanoparticles: Biomedical applications as theranostic agents for cancer, Pages 161-242, in: Design of Nanostructures for Theranostics Applications. Edited by: Alexandru Mihai Grumezescu ISBN: 978-0-12-813669-0, Elsevier 2018

3. Elena Alina Moacă, Elena Dorina Coricovac, Codruta Marinela Soica, Iulia Andreea Pinzaru, Cornelia S Păcurariu, Cristina Adriana Dehelean. Chapter 12 - Preclinical aspects on magnetic iron oxides nanoparticles and their interventions as anticancer agents: enucleation, apoptosis and other mechanism, DOI: 10.5772/intechopen.74176, in: Iron ores and iron oxide materials, Edited by: Dr. Volodymyr Shatokha, ISBN 978-1-78923-320-9, InTech 2018

4. Codruţa Şoica, Diana Antal, Florina Andrica, Roxana Băbuţa, Alina Moacă, Florina Ardelean, Roxana Ghiulai, Stefana Avram, Corina Danciu, Dorina Coricovac, Cristina Dehelean. Lupan-Skeleton Pentacyclic Triterpenes with Activity against Skin Cancer: Preclinical Trials Evolution, DOI: 10.5772/intechopen.68908, in: Unique Aspects of Anti-cancer Drug Development, Edited by: Jolanta Natalia Latosinska and Magdalena Latosinska, ISBN 978-953-51-3348-3, Print ISBN 978-953-51-3347-6, InTech 2017

5. Stefana Avram, Roxana Ghiulai, Ioana Zinuca Pavel, Marius Mioc, Roxana Babuta,Mirela Voicu, Dorina Coricovac, Corina Danciu, Cristina Dehelean, Codruta Soica. Phytocompounds targeting cancer angiogenesis using the chorioallantoic membrane assay, in: Phytochemistry - Natural Products and Cancer, ISBN 978-953-51-3314-8, Print ISBN 978-953-51-3313-1, Intech 2017

6. Corina Danciu, Suciu Oana, Diana Simona Antal, Florina Ardelean, Aimée Rodica Chiș, Codruța Șoica, Florina Andrica, Cristina Dehelean, Vlaicu Brigitha. New insights regarding the potential health benefits of isoflavones, pages: 257-286, in: Flavonoids, Edited by: José Justino, ISBN 978-953-51-5338-2, Intech 2017

7. Danciu Corina, Soica Codruta, Antal Diana, Alexandra Popescu, Stefana Avram, Roxana Ghiulai, Ioana Zinuca Pavel, Minda Daliana, Cristina Dehelean. An update of natural compounds and their modern formulations for the management of malignant melanoma, pages: 211-253, in: Phytochemistry - Natural Products and Cancer, Edited by: Farid A. Badria, ISBN 978-953-51-3314-8, Print ISBN 978-953-51-3313-1, Intech 2017

8. Dorina E. Coricovac, Cristina A. Dehelean. Chapter 1 - Pathological Aspects with Global Impact Induced by Toxicants at Cellular Level, pages 3-21, DOI: 10.5772/59945, in: Toxicology Studies – Cells, Drugs and Environment, Edited by: Ana Cristina Andreazza and Gustavo Scola, ISBN 978-953-51-2140-4, InTech 2015

9. Codruţa Şoica, Cristina Trandafirescu, Florin Borcan, Corina Danciu, Georgeta Simu, Cristina Dehelean. Nanoformulations with cyclodextrins as carriers for skin targeting of active drugs, in: Biotechnology-Novel Drug Delivery, Volume 8, pages: 29-56, Series ISBN: 1-62699-015-8, Vol. ISBN No.: 1-62699-023-9, Studium press LLC, Houston, USA 2014

10. Corina Danciu, Cristina Dehelean, Codruta Soica. Chapter 2 - Natural Compound Genistein: From Consecrated to New Utilizations and Formulations, in: Biotechnology - Drug Discovery, Volume 7, pages: 43-61, Series ISBN: 1-62699-022-0, Vol. ISBN: 1-62699-015-8, Studium Press, LLC, Houston, USA 2014

Feb 2022 DEHELEAN CRISTINA ADRIANA