Virusologie Curs Concis

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    .

    irusologi este pentru med i cin ce e ce e s te fizic nuclearii pentru fizi i icad Stefan S Nicolau

    .A cesta nu este un manual de virusologie medicala, Este un rezum at al cunostintelor

    I .

    Microbii au fost primele organisme vii aparute pe ,parnan~.Microbii au precedat plantele i animalele n peste 3 m ilioane de ani i au contribnit la fonnarea biosferei am t dinpunct ..d e vedere evolutionist c a t .~ i din punct de vedere ~_cologic. Se estimeazs c a speciilebscteriene ~eazi 60% din biomass p a r n a n t u l u i Ceea ce cunoastem azi reprezintanumai 0.5% din totalnlde circa 2-3 mil iarde specii microbiene care probabil exista,Virusurile, sjml1ar microb ilor , sunt, microorgaDj~e p rokB rio te . e u potential patogen. '.Virusurile au apanrt consecutiv bacteriilor si, implicit, consecutiv evolupei eukariotelor,ExistA yirusuri ale . bacter ii1or . (bacter iofagi ), _ yiru su ri -a Je p la nte loT si ale animalelor.Dintre acestea din urma fac pane circa 20 f am iiii e ll p ote n'j ia l p ato gen p en tr u om .V i ru su rile se d eo se be sc d e b ac te rii prin~

    parazitism exclusiv intracelular dependent de_sursele de energie ale celulei (virusurile nu au mitocondrii)

    ... .dependenta de mecanismele de sinteza p ro te ica (vi ru su ri le nu au ribozomi) alecelulelo r parazitate; .

    cul tiv ate numa i pe substraruri celulare vii;organizare s imp la d ic ta te de codificarea informatiei g en etice d e specie unica de 'acid nucleic: .~ -da ribovirusuri si A D ~ la dezoxiribovirusuri;

    e lemen ta re neces ar e studenrului in med icin e p en tm 'a in teleg e 'patogenia prevenirea ~itra tam en tu l u nn i se gm en t im p orta nt al pato logiei infectioase: virozele, , ' .. , .

    2 .. ornr iIINTRODUCTnf:

    . .

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