Metodologia Cercet stiintif

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    Copyright 2008 The Endocrine Society

    Kondrashova, A. et al. J Clin Endocrinol Metab 2008;93:729-734

    FIG. 1. Frequency of TPOAb and TGAb in schoolchildren in Russian Karelia (black bars)and in Finland (white bars)

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    Copyright 2008 The Endocrine Society

    Checchi, S. et al. J Clin Endocrinol Metab 2008;93:465-469

    FIG. 2. L-T4 requirement ({micro}g/kg {middle dot} d) in hypothyroid patients on L-T4replacement therapy according to the PCA status (positive or negative)

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    Copyright 2008 The Endocrine Society

    Checchi, S. et al. J Clin Endocrinol Metab 2008;93:465-469

    FIG. 3. L-T4 daily requirement in 73 PCA-positive patients submitted to gastric biopsyaccording to the histological results (normal mucosa or atrophic changes)

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    TABLE 1.Clinical characteristics and androgen levels of the PCOS and

    control groups

    PCOS (n = 83) Controls (n = 39) Pvalue

    Age (yr) 27.84.7 27.85.6 0.785

    BMI (kg/m) 30.45.9 29.14.8 0.140

    WHR 0.82 0.07 0.800.04 0.191

    Testosterone (nmol/liter) 2.21 1.44 1.320.62

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    Karavitaki N, Trifanescu R, Wass J, Clin Endocrinol, 2006; 65:524

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    Mean ({+/-}SE) Percentage Change from Baseline to 1 Year

    in Glycated Hemoglobin, Fasting Plasma Glucose,

    Postprandial Glucose, and Body Weight (Panel A) and Mean

    (+SD) Hypoglycemic-Event Rate (Panel B)

    Holman R et al. N Engl J Med 2007;357:1716-1730

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    Holman R et al. N Engl J Med 2007;357:1716-1730

    Adverse Events

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    FIG. 1. Glucose and log GH levels afteran oral glucose load in prepubertal girls

    (A) (group 1: Tanner 1),early to midpubertal girls (B) (group 2:

    Tanner 2 and 3),mid to late pubertal girls (C) (group 3:

    Tanner 4 and 5),prepubertal and early pubertal boys (D)

    (group 1: Tanner 1 and 2),midpubertal boys (E) (group 2: Tanner 3and 4), and late pubertal boys (F) (group

    3: Tanner 5)

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